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BACKGROUND: The Republic of South Africa is an associated member of the JINR already for 10 years. Currently, scientists from the RSA participate in different themes of the Topical Plan for JINR Research and International Cooperation including theory of nuclear structure and reactions, experimental elementary particle physics, relativistic nuclear physics, synthesis and properties of nuclei at the stability limits, accelerator complex of ion beams of stable and radioactive nuclides, investigations in the field of nuclear physics with neutrons, investigations of condensed matter by modern neutron scattering methods, networking, computing, computational physics, educational programme etc. On the initiative of the JINR and South Africa institutions three South Africa-JINR Symposiums were already organized, namely the 1st Symposium at Skukuza, Kruger National Park, in February 2007, the 2nd Symposium at JINR Dubna, in September 2010; the 3rd Symposium at Blaauwklippen wine farm, Stellenbosch, in November 2012. These successful scientific meetings have established new and fruitful collaborations between both physical communities. PRESENT MEETING: The Joint Institute for Nuclear Research will host the 4th South Africa-JINR Symposium in Dubna in the period September 21-25, 2015, which will be dedicated to the celebration of the 60th anniversary of the JINR and 10th anniversary of signing the Memorandum of Understanding between the Government of the Republic of South Africa and the Joint Institute for Nuclear Research. The Symposium will discuss the scope, success and prospective of experimental, theoretical and applied physics at the JINR and in South Africa institutions and a special attention will be devoted to scientific facilities on both sides. The Symposium will include three days of plenary and discussion sessions, namely September 21-23, 2015. September 24, 2015 is presumed for an excursion to Moscow and September 25, 2015 is planned for visit of the JINR Laboratories. The goal of the meeting is to present main results of the SA-JINR collaboration, extend the scientific and technological cooperation among the JINR and South Africa institutions and to attract young scientists from both sides to running joined research projects. The Symposium program will cover new developments in the field of particle physics, nuclear physics, applied nuclear physics, condensed matter physics, bio-monitoring project and physics of underground laboratories. Speakers of each of 12 sessions will be selected by the coordinators of the session. The main idea is to have speakers from both South Africa and JINR and in particular cases, an expert from the field from other institute. Students from both sides will be given an opportunity to make short presentations on their research during the student session. It is believed that symposium will initiate opportunities to establish new areas scientific cooperation and extend the existing cooperation among physicists from South Africa and the JINR. Organizing Committee V. Voronov (JINR) co-chairman voronov@theor.jinr.ru R. Adam (SKA) co-chairman rob@ska.ac.za F. Šimkovic (JINR) vice-chairman simkovic@theor.jinr.ru S. Wyngaardt (Uni-Stellenbosch) vice-chairman shaunmw@sun.ac.za D. Kamanin (JINR) kamanin@jinr.ru J. Cleymans (Uni-Cape Town) jean.cleymans@gmail.com N. Jacobs (Uni-Stellenbosch noel@ma2.sun.ac.za S. Pakuliak (JINR) pakuliak@uc.jinr.ru S. Rakityansky (Uni-Pretoria) rakitsa@science.unisa.ac.za R. Newman (Uni-Stellenbosch) rtnewman@sun.ac.za E. Kolganova (JINR) kea@theor.jinr.ru S. Nedelko (JINR) nedelko@theor.jinr.ru O. Matyukhina (JINR) secretary omatyukhina@jinr.ru