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The Conference on Mathematical Biology and Bioinformatics brings together scientists and students from Russia and all over the world to discuss recent advances in mathematical and computational biology, bioinformatics and applications. The conference will be held at Pushchino Research Center, September 7-13, 2008. The conference has following objectives: To communicate the best of recent advances in mathematical modelling approaches in the life sciences and to identify key targets of future work. To provide a platform for young researchers.