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Medical doctors undergo an extensive and fundamental education, yet their decision-making in uncertain conditions may be subject to cognitive biases, such as the framing effect. Susceptibility to the framing effect was studied in Russian (N=48) and Azerbaijani (N=40) doctors. Both groups were educated under equivalent systems in the same language. Therefore, the established dissimilarities may be attributed to cross-cultural differences. Participants completed the following measures. (1) The Asian Disease Problem. (2) The Personality Risk Factors Questionnaire, assessing rationality and riskiness. (3)The Melbourne Decision Making Questionnaire, assessing vigilance, hypervigilance, procrastination and buck-passing. (4) Budner’s questionnaire for assessing tolerance and intolerance of ambiguity. The framing effect was shown in 52% of the Azerbaijani doctors and in 36% of the Russian doctors. Azerbaijani doctors were more prone to ineffective patterns of coping with decisional conflict: buck-passing, procrastination and hypervigilance. Medical doctors in Azerbaijan showed more intolerance to uncertainty that is linked with unproductive coping patterns in both samples. Azerbaijani doctors , demonstrating the framing effect, were less risk-ready and showed higher hypervigilance. In Russian doctors, demonstrating the framing effect, riskiness is positively related to tolerance of uncertainty, while rationality is associated with vigilance. Supported by the Russian Foundation for Basic Research, project 17-06-00130