ИСТИНА

Functionalized organophosphorus acids and their derivatives with heterocyclic and unsaturated fragments are of great interest as effective chelating ligands and perspective bioactive substances with various properties. These acids are well-known analogs of hydroxyl (amino)carbonic acids and natural pyrophosphates. We have developed the convenient methods of synthesis of new functionalized mono- and bisorganophosphorus acids and their derivatives including heterocyclic, aromatic and unsaturated fragments as well as hydroxyl, amino, and carboxyl groups using as starting compounds the trimethylsilyl esters of several trivalent phosphorus acids and functionalized alkenes, aldehydes, and carbonic acids [1]. The trimethylsilyl esters of functionalized organophosphorus acids easily react with methanol or sodium methylate in methanol yielding the new water soluble organophosphorus acids or their salts which are presented. KOST-2015 HETEROCYCLIC CONGRESS.Lomonosov Moscow State University, Moscow, 18-23 October 2015. Book of Abstracts. P069. P. 333.