ИСТИНА

Recently bacteriolitic activity of human interleukin-2 was observed. Interleukin-2 has a specificity to gram-negative Escherichia coli and has not activity on common gram-positive microorganisms, such as Micrococcus luteus, Bacillus subtilis. Bacteriolitic activity of human interleukin-2 was investigated for various microorganisms: Escherichia coli, Bifidobacterium bifidum, Lactobacillus plantarum. Studies were carried out at different values of pH, ionic strength, concentration of surfactant. In particular, bacteriolitic activity of interleukin-2 was investigated in the presence of sodium dodecyl sulfate, witch is a part of a number of medications. It was found that 0.5 mg/ml of dodecyl has no effect on interleukin-2 bacteriolitic properties. Dodecyl sulfate at the same concentrations itself in the absence of interleukin-2 has no influence on bacteria lysis.