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We use a gas dynamics approach to numerical modeling of Molecular Cloud-Cloud Collision that leads to formation conditions for triggering protostars in the interstellar medium. The calculations were performed according to different colliding scenarios between two dissimilar clouds. In numerical experiments non-identical oppositely moving molecular clouds collide with each other in head-on motion at relative velocity which could vary within the range of 5 to 25 km·s-1. The post-collision clouds’ shaping and the compression oscillation in bow-shock core depend on initial conditions of colliding. In situations with insufficiently smoothness of pressure/energy fields between clouds and ISM, the energy disturbance in a compressed core with originated clumps leads to coherent perturbations both shock layer and in outside space. The paper gives a morphological analysis of inclusions in a bowshock layer, perturbations and turbulization of matter, fragmentation and disruption of gas remnants. Cloud-Cloud Collision effects have been compared by different scenarios of MCs collision. A parallel Eulerian code based on high resolution grids is used to perform numerical experiment on high-performance computers.