ИСТИНА

Enzymatic oxidative polymerization of 3,4-ethylendioxytiophene (EDOT) was carried out using “soft” natural polyelectrolyte DNA as a template. As known, phosphate groups of DNA bind other molecules via electrostatic interactions or/and hydrogen bonding, thus DNA can be served as a dopant of the main chain of PEDOT. A commercially available sodium deoxyribonucleate (Derinat) containing DNA molecules from 50 to 900 base pairs was used. Conductive biocompatible interpolymer complex PEDOT/DNA was obtained by enzymatic EDOT polymerization with atmospheric oxygen as a terminal oxidant. High redox potential fungal laccase Trametes hirsuta was used as a biocatalyst of the reaction. The resulting biocomposite formed a stable aqueous-dispersible system. PEDOT/DNA conductivity measured by standard four-point method was of ~0,15 mS/cm. Some physicochemical characteristics of obtained complex and its morphology have been investigated. PEDOT/DNA complex may be used in various biodevices, for example, biosensors, flexible biocompatible neurointerfaces, implantable supercapacitors and others.