ИСТИНА

Self-assembly of macromolecules possessing local amphiphilicity is characterized by very rich morphological behavior. Among them are many thermosensitive polymers (as PNIPAm-based systems), biopolymers and amphiphilic molecular brushes. The shape and size of macromolecular aggregates as well as single condensed macromolecules depend on the molecular characteristics and external conditions in solution.1,2 In particular, the formation of vesicle particles with very thin shell is observed for some amphiphilic homopolymers with hydrophobic and polar parts in monomer units separated by a certain distrance. In the lecture, a theoretical analysis of morphology of single amphiphilic homopolymers and diblock copolymers in solution is presented. Amphiphilic monomer units are described as dimers with solvophobic and solvophilic parts connected by a fixed length bond. It is the surface activity of amphiphilic monomers that lead to a variety of spacial structures which are rich in surfaces. The solvophobic blocks in collapsed diblock copolymer macromolecules tend to intramolecular segregation from amphiphilic blocks. The calculated morphology diagrams are presented in comparison with the computer simulation data.