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The detection of microorganisms on the cosmic bodies of the Solar System is a great importance for understanding the problem of the origin of life on Earth, determining its source, and identifying the conditions that contributed to its origin. At present, it is difficult to create specialized laboratories conducting research on the search for living microorganisms on the surface of planets or other space bodies, both formed in the Solar System or captured by the attraction of the Sun from interstellar space. Existing experiments on descent vehicles, as well as planetary rovers, allow to conduct research on the search for living microorganisms on the surface of planets and their satellites, but in a limited area near the landing site. Given the fact that rare forms of life, as a rule, form colonies that exist in a limited space in hard-to-reach places, the task of finding microorganisms is even more complicated. In this presentation, for the search of biological objects, the method of remote sensing of the surface of space objects by flashes of light is considered. A signpost of the existence of bioactivity in this case is the detection of specific fluorescence of microorganisms when the object of study is illuminated by the light which exciting of the fluorescence radiation. It is shown that such studies can be carried out directly from outer space, both on the flight paths of a spacecraft near a space object, or from its satellite orbit, or on the surface of a space body after landing the descent vehicle. In the case of the detection of microorganisms, a detailed study of their biological properties and their habitat is possible using fluorescent analysis methods. To do this, it is sufficient significantly to improve the duration of the probing radiation, or to carry out multiple measurements of the same object in order to achieve the required measurement accuracy, it is possible since during such measurements biological objects are not destroyed