ИСТИНА

This paper describes the main features of newest version of the Proton-Carbon Ion Radiation Therapy Planning System (PIPLAN). The PIPLAN 2021 code was assigned for precise Monte Carlo treatment planning for heterogeneous areas, including lung, head and neck location. Two various computer methods are used to modeling the interactions between the proton and carbon ion beam and the patient's anatomy to determine the spatial distribution of the radiation physical and biological dose. The first algorithm is based on the use of the RTS&T 2021 high precision radiation transport code system. The second algorithm is based on the original Ulmer’s method for primary proton beam and adapted Ulmer’s algorithm designed for primary carbon ion beam with energy in the range 100-450 MeV/u.