ИСТИНА

Nanoparticles (NPs) have a great potential for various applications ranging from the pharmaceutical and cosmetic industries to modern medicine for the purpose of diagnostics and therapy [1]. Using red blood cells (RBCs) as natural transport agents for systemic drug delivery by placing NPs onto the RBC surface is considered a new paradigm in modern medicine that possesses great potential. Safety issues and verification of the effectiveness of NPs used in biomedical applications have been examined in many articles [2]. The aim of this work is to study the effect of various NPs on the microrheological properties of RBCs after incubation of whole blood samples with these NPs at various concentrations in vitro using laser-optical methods.