ИСТИНА

Boron nanostructures have many applications in various fields, including medical applications. Nanoparticles of nitride, carbide and elemental boron are among the most widely studied boron compounds in medicinal chemistry. The paper will present in detail modern aspects in the synthesis and physicochemical properties of boron nanostructures for their use in in vitro/in vivo experiments for boron neutron capture therapy [1, 2]. For the successful application of boron nanostructures in boron neutron capture therapy, it is important to understand which precursors were used for synthesis, since the composition of the final form of a nanopreparation directly affects the main criterion for their effectiveness - bioavailability. It is important to correctly select a material for the synthesis of nanoparticles, which, along with efficiency, should demonstrate biocompatibility and the absence of toxicity, as well as a method for implementing the synthesis of nanoparticles. Evaluation of the shape, morphology, size, and composition of the surface is an integral part of the characteristics of boron nanostructures, since they are important for further stages of modification by biologically active molecules [3].