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The glandular and nervous systems were studied in D. ditremum from Oncorhynchus nerka. Ultra structure of the glandular system evident their belonging to frontal gland. Perikarya of the frontal gland create the glandular envelope around the brain of plerocercoid. Glandular cells have specialized contacts like electrical synapses with neurons of the brain. It was found that the frontal gland has specialized pores in the tegument, encircled by a system of specialized contacts. Pores in the tegument co-localized with sensory endings: the ciliate and unciliate receptors. In subtegument the membranes of glandular processes have contacts like electrical synapses with the neurites and make desmosome-like contacts with muscles. Our investigation evident the presence of the innervation of the glandular cells via the central neurons. Consequently the cestodes frontal glands are functioning under the control of the central nervous system.