ИСТИНА

Варижук Анна Михайловна пользователь

доктор химических наук с 2018 года

ФГБУ «Федеральный научно-клинический центр физико-химической медицины Федерального медико-биологического агентства»

Соавторы: Pozmogova G.E., Tsvetkov V.B., Aralov A.V., Зацепин Т.С., Анохин К.В., Барыкина Н.В., Позмогова Г.Е., Субач О.М., Субач Ф.В., Петкевич К., Сотсков В.П., Kaluzhny D.N., Malyshev A. показать полностью..., Turaev A.V., Ениколопов Г.Н., Плюснин В.В., Tatarinova O.N., Беляев Е.С., Груздева А.М., Ивашкина О.И., Basmanov D., Boiko K.M., Bolden D.S., Isaakova E.A., Korzhenevskiy D., Kostyukevich Y.I., Nikolaeva A., Rakitina T.V., Shpakovski G.V., Smirnov I.P., Баранов М.С., Баринов Н., Власкина А.В., Дедков В.Г., Ивлева О.А., Клинов Д.В., Лагарькова М.А., Подгорский В.В., Северов В.В., Смирнов И., Смирнов И.В., Тимофеев А.В., Флорентьев В.Л., Шипулин Г.А., Aseychev A.V., Bespyatykh J., Bogorodsky D., Borisova O.F., Borshevsky V.I., Chizhov A.O., Chuvilin A., Chuvilin A.N., Fisunov G.Y., Grokhovsky S.L., June 2., Kharlampieva D.D., Kozhemyako V.B., Lazarenko V.A., Manuvera V.A., Markina N., Podgornyi O.V., Portugues R.F., Povarova N., Rakitina D.V., Shchyolkina A.K., Vanyushkina A., Vlasenok M.A., You K., Zaitsev S., Балеева Н.С., Богомазова А.Н., Вишняков И.Е., Головин А.В., Гущина Е., Доронин Д.А., Доронин Д.С., Дубровин Е.В., Есипов Д.С., Захаржевская Н.Б., Кириллова Ю.Г., Куницына Т.А., Лазуткин А.А., Лисицын Ф.В., Мельник Д.М., Михайлов С.Н., Мяснянко И.Н., Новиков Р.А., Петрунина А.А., Протопопова А.Д., Прусаков К.А., Сардушкин М.В., Смирнов И.Ф., Тевяшова А.Н., Фарзан В.М., Ходарович Ю.М., Чефанова Е.С., Шитиков Е.А.

35 статей, 1 доклад на конференции

Количество цитирований статей в журналах по данным Web of Science: 307, Scopus: 304

IstinaResearcherID (IRID): 376484603

ResearcherID: Y-7558-2019

Scopus Author ID: 26026701500

Деятельность

• Статьи в журналах

  • • 2021 Phenoxazine pseudonucleotides in DNA i-motifs allow precise profiling of small molecule binders by fluorescence monitoring
    • Tsvetkov Vladimir B., Turaev Anton V., Petrunina Nataliia A., Melnik Denis M., Khodarovich Yuriy M., Pozmogova Galina E., Zatsepin Timofei S., Varizhuk Anna M., Aralov Andrey V.
    • в журнале The Analyst, издательство Royal Society of Chemistry (United Kingdom) DOI
  • 
    • 2020 Aureolic Acid Group of Agents as Potential Antituberculosis Drugs
    • Bespyatykh J., Bespiatykh D., Malakhova M., Klimina K., Bespyatykh A., Varizhuk A., Tevyashova A., Nikolenko T., Pozmogova G., Ilina E., Shitikov E.
    • в журнале Antibiotics, издательство MDPI Publishing (Basel, Switzerland, Switzerland), том 9, № 10, с. 715-715
  • 
    • 2020 FGCaMP7, an Improved Version of Fungi-Based Ratiometric Calcium Indicator for In Vivo Visualization of Neuronal Activity
    • Barykina Natalia V., Sotskov Vladimir P., Gruzdeva Anna M., Kure Wu You, Portugues Ruben, Subach Oksana M., Chefanova Elizaveta S., Plusnin Viktor V., Ivashkina Olga I., Anokhin Konstantin V., Vlaskina Anna V., Korzhenevskiy Dmitry A., Nikolaeva Alena Y., Boyko Konstantin M., Rakitina Tatiana V., Varizhuk Anna M., Pozmogova Galina E., Subach Fedor V.
    • в журнале International Journal of Molecular Sciences, издательство MDPI (Basel, Switzerland), том 21, № 8, с. 3012
  • 
    • 2020 Genomic DNA i-motifs as fast sensors responsive to near-physiological pH microchanges
    • Turaev Anton V., Isaakova Ekaterina A., Severov Vjacheslav V., Bogomazova Alexandra N., Zatsepin Timofei S., Sardushkin Makar V., Aralov Andrey V., Lagarkova Maria A., Pozmogova Galina E., Varizhuk Anna M.
    • в журнале Biosensors and Bioelectronics, издательство Pergamon Press Ltd. (United Kingdom) DOI
  • 
    • 2020 Novel Genetically Encoded Bright Positive Calcium Indicator NCaMP7 Based on the mNeonGreen Fluorescent Protein
    • Subach Oksana M., Sotskov Vladimir P., Plusnin Viktor V., Gruzdeva Anna M., Barykina Natalia V., Ivashkina Olga I., Anokhin Konstantin V., Nikolaeva Alena Y., Korzhenevskiy Dmitry A., Vlaskina Anna V., Lazarenko Vladimir A., Boyko Konstantin M., Rakitina Tatiana V., Varizhuk Anna M., Pozmogova Galina E., Podgorny Oleg V., Piatkevich Kiryl D., Boyden Edward S., Subach Fedor V.
    • в журнале International Journal of Molecular Sciences, издательство MDPI (Basel, Switzerland), том 21, № 5, с. 1644 DOI
  • 
    • 2020 Phenoxazine-based scaffold for designing G4-interacting agents
    • Tsvetkov Vladimir B., Varizhuk Anna M., Lizunova Sofia A., Nikolenko Tatiana A., Ivanov Igor A., Severov Vjacheslav V., Belyaev Evgeny S., Shitikov Egor A., Pozmogova Galina E., Aralov Andrey V.
    • в журнале Organic and Biomolecular Chemistry, издательство Royal Society of Chemistry (United Kingdom), том 18, № 31, с. 6147-6154 DOI
  • 
    • 2020 Short Duplex Module Coupled to G-Quadruplexes Increases Fluorescence of Synthetic GFP Chromophore Analogues
    • Zaitseva Snizhana O., Baleeva Nadezhda S., Zatsepin Timofei S., Myasnyanko Ivan N., Turaev Anton V., Pozmogova Galina E., Khrulev Alexei A., Varizhuk Anna M., Baranov Mikhail S., Aralov Andrey V.
    • в журнале Sensors, издательство MDPI (Basel, Switzerland), том 20, № 3, с. 915 DOI
  • 
    • 2020 Transcription-facilitating histone chaperons interact with genomic and synthetic G4 structures
    • Pavlova I.I., Tsvetkov V.B., Isaakova E.A., Severov V.V., Khomyakova E.A., Lacis I.A., Lazarev V.N., Lagarkova M.A., Pozmogova G.E., Varizhuk A.M.
    • в журнале International Journal of Biological Macromolecules, издательство Elsevier BV (Netherlands), том 160, с. 1144-1157
  • 
    • 2019 Benzothiazole-based cyanines as fluorescent “light-up” probes for duplex and quadruplex DNA
    • Turaev A.V., Tsvetkov V.B., Tankevich M.V., Smirnov I.P., Aralov A.V., Pozmogova G.E., Varizhuk A.M.
    • в журнале Biochimie, издательство Elsevier BV (Netherlands), том 162, с. 216-228
  • 
    • 2019 DNA G‐Quadruplexes (G4s) Modulate Epigenetic (Re)Programming and Chromatin Remodeling
    • Varizhuk A., Isaakova E., Pozmogova G.
    • в журнале BioEssays, издательство John Wiley & Sons Inc. (United States), том 41, № 9, с. 1900091-1900091
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    • 2019 DNA i-Motifs With Guanidino-i-Clamp Residues: The Counterplay Between Kinetics and Thermodynamics and Implications for the Design of pH Sensors
    • Tsvetkov Vladimir B., Zatsepin Timofei S., Turaev Anton V., Farzan Valentina M., Pozmogova Galina E., Aralov Andrey V., Varizhuk Anna M.
    • в журнале Computational and Structural Biotechnology Journal, том 17, с. 527-536 DOI
  • • 2018 Efficient silica synthesis from tetra(glycerol)orthosilicate with cathepsin- and silicatein-like proteins
    • Povarova Natalia V., Barinov Nikolay A., Baranov Mikhail S., Markina Nadezhda M., Varizhuk Anna M., Pozmogova Galina E., Klinov Dmitry V., Kozhemyako Valery B., Lukyanov Konstantin A.
    • в журнале Scientific reports, издательство Nature Publishing Group (United Kingdom), том 8, № 1
  • • 2018 Genetically encoded calcium indicator with NTnC-like design and enhanced fluorescence contrast and kinetics
    • Doronin D.A., Barykina N.V., Subach O.M., Sotskov V.P., Plusnin V.V., Ivleva O.A., Isaakova E.A., Varizhuk A.M., Pozmogova G.E., Malyshev A.Y., Smirnov I.V., Piatkevich K.D., Anokhin K.V., Enikolopov G.N., Subach F.V.
    • в журнале BMC Biotechnology, издательство BioMed Central (London), том 18, № 1 DOI
  • 
    • 2018 NTnC-like genetically encoded calcium indicator with a positive and enhanced response and fast kinetics
    • Natalia Barykina, Doronin Danila A., Subach Oksana M., Sotskov Vladimir P., Plusnin Viktor V., Ivleva Olga A., Gruzdeva Anna M., Kunitsyna Tatiana A., Ivashkina Olga I., Lazutkin Alexander A., Malyshev Aleksey Y., Smirnov Ivan V., Varizhuk Anna M., Pozmogova Galina E., Piatkevich Kiryl D., Anokhin Konstantin V., Grigori Enikolopov, Subach Fedor V.
    • в журнале Scientific reports, издательство Nature Publishing Group (United Kingdom), том 8, № 15233 DOI
  • 
    • 2018 Polymorphism of G4 associates: from stacks to wires via interlocks
    • Varizhuk Anna M., Protopopova Anna D., Tsvetkov Vladimir B., Barinov Nikolay A., Podgorsky Victor V., Tankevich Maria V., Vlasenok Maria A., Severov Vyacheslav V., Smirnov Igor P., Dubrovin Evgeniy V., Klinov Dmitry V., Pozmogova Galina E.
    • в журнале Nucleic Acids Research, издательство Oxford University Press (United Kingdom), том 46, № 17, с. 8978-8992 DOI
  • 
    • 2018 The structural diversity of C-rich DNA aggregates: unusual self-assembly of beetle-like nanostructures
    • Protopopova A.D., Tsvetkov V.B., Varizhuk A.M., Barinov N.A., Podgorsky V.V., Klinov D.V., Pozmogova G.E.
    • в журнале Physical Chemistry Chemical Physics, издательство Royal Society of Chemistry (United Kingdom), том 20, № 5, с. 3543-3553
  • 
    • 2018 i-Clamp phenoxazine for the fine tuning of DNA i-motif stability
    • Tsvetkov Vladimir B., Zatsepin Timofei S., Belyaev Evgeny S., Kostyukevich Yury I., Shpakovski George V., Podgorsky Victor V., Pozmogova Galina E., Varizhuk Anna M., Aralov Andrey V.
    • в журнале Nucleic Acids Research, издательство Oxford University Press (United Kingdom), том 46, № 6, с. 2751-2764 DOI
  • 
    • 2017 Anti-HIV Activities of Intramolecular G4 and Non-G4 Oligonucleotides
    • Prokofjeva M., Tsvetkov V., Basmanov D., Varizhuk A., Lagarkova M., Smirnov I., Prusakov K., Klinov D., Prassolov V., Pozmogova G., Mikhailov S.N.
    • в журнале Nucleic acid therapeutics, издательство Mary Ann Liebert, Inc. (New Rochelle, NY, United States), том 27, № 1, с. 56-66
  • • 2017 Conformational polymorphysm of G-rich fragments of DNA Alu-repeats
    • Sekridova A.V., Varizhuk A.M., Tatarinova O.N., Severov V.V., Barinov N.A., Smirnov I.P., Lazarev V.N., Klinov D.V., Pozmogova G.E.
    • в журнале Biochemistry (Moscow), издательство Pleiades Publishing, Ltd (Road Town, United Kingdom), том 11, № 1, с. 62-71
  • 
    • 2017 Conformational polymorphysm of G-rich fragments of DNA Alu-repeats. II. The putative role of G-quadruplex structures in genomic rearrangements
    • Varizhuk A.M., Sekridova A.V., Tankevich M.V., Podgorsky V.S., Smirnov I.P., Pozmogova G.E.
    • в журнале Biochemistry, Supplemental Series B, издательство Maik Nauka/Interperiodica Publishing (Russian Federation), том 11, № 2, с. 146-153
  • 
    • 2017 Green fluorescent genetically encoded calcium indicator based on calmodulin/M13-peptide from fungi
    • Barykina Natalia V., Subach Oksana M., Piatkevich Kiryl D., Jung Erica E., Malyshev Aleksey Y., Smirnov Ivan V., Bogorodskiy Andrey O., Borshchevskiy Valentin I., Varizhuk Anna M., Pozmogova Galina E., Boyden Edward S., Anokhin Konstantin V., Enikolopov Grigori N., Subach Fedor V.
    • в журнале PLoS ONE, издательство Public Library of Science (United States), том 12, № 8, с. 0183757 DOI
  • • 2017 Interaction of Bacteroides fragilis Toxin with Outer Membrane Vesicles Reveals New Mechanism of Its Secretion and Delivery
    • Zakharzhevskaya Natalya B., Tsvetkov Vladimir B., Vanyushkina Anna A., Varizhuk Anna M., Rakitina Dania V., Podgorsky Victor V., Vishnyakov Innokentii E., Kharlampieva Dania D., Manuvera Valentin A., Lisitsyn Fedor V., Gushina Elena A., Lazarev Vassili N., Govorun Vadim M.
    • в журнале Frontiers in Cellular and Infection Microbiology, издательство Frontiers Media S.A. (Lausanne, Switzerland), том 7, № 2 DOI
  • 
    • 2017 Synthesis of Oligonucleotides Containing Novel G-clamp Analog with C8-Tethered Group in Phenoxazine Ring: Implication to qPCR Detection of the Low-Copy Kemerovo Virus dsRNA
    • Varizhuk Anna M., Zatsepin Timofei S., Golovin Andrey V., Belyaev Evgeny S., Kostyukevich Yury I., Dedkov Vladimir G., Shipulin German A., Shpakovski George V., Aralov Andrey V.
    • в журнале Bioorganic and Medicinal Chemistry, издательство Pergamon Press Ltd. (United Kingdom), том 25, № 14, с. 3597-3605 DOI
  • 
    • 2017 The expanding repertoire of G4 DNA structures
    • Varizhuk A., Ischenko D., Tsvetkov V., Novikov R., Kulemin N., Kaluzhny D., Vlasenok M., Naumov V., Smirnov I., Pozmogova G.
    • в журнале Biochimie, издательство Elsevier BV (Netherlands), том 135, с. 54-62
  • 
    • 2016 A Solution to the Common Problem of the Synthesis and Applications of Hexachlorofluorescein Labeled Oligonucleotides
    • Chuvilin A.N., Smirnov I.P., Mosina A.G., Varizhuk A.M., Pozmogova G.E.
    • в журнале PLoS ONE, издательство Public Library of Science (United States), том 11, № 11, с. 0166911-0166911
  • 
    • 2016 A new design for a green calcium indicator with a smaller size and a reduced number of calcium-binding sites
    • Barykina NV, Subach OM, Doronin DA, Sotskov VP, Roshchina MA, Kunitsyna TA, Malyshev AY, Smirnov IV, Azieva AM, Sokolov IS, Piatkevich KD, Burtsev MS, Varizhuk AM, Pozmogova GE, Anokhin KV, Subach FV, Enikolopov GN
    • в журнале Scientific reports, издательство Nature Publishing Group (United Kingdom), том 6, с. 34447 DOI
  • 
    • 2016 Chiral Acyclic PNA Modifications: Synthesis and Properties
    • Varizhuk A.M., Dezhenkov A.V., Kirillova Y.G.
    • в журнале Studies in Natural Products Chemistry, том 47, с. 261-305
  • 
    • 2016 G4 Aptamers: Trends in Structural Design
    • Varizhuk A., Ilyinsky N., Smirnov I., Pozmogova G.
    • в журнале Mini-Reviews in Medicinal Chemistry, том 16, № 16, с. 1321-1329
  • 
    • 2015 A Universal Base in a Specific Role: Tuning up a Thrombin Aptamer with 5-Nitroindole
    • Tsvetkov Vladimir B., Varizhuk Anna M., Pozmogova Galina E., Smirnov Igor P., Kolganova Natalia A., Timofeev Edward N.
    • в журнале Scientific reports, издательство Nature Publishing Group (United Kingdom), том 5, с. 16337 DOI
  • • 2015 Polyanionic Carboxyethyl Peptide Nucleic Acids (ce-PNAs): Synthesis and DNA Binding
    • Kirillova J.G., Boyarskaya N., Dezhenkov F., Tankevich, Prokhorov I., Varizhuk, Eremin S., Esipov D.S., Smirnov I., Pozmogova G.E.
    • в журнале PLoS ONE, издательство Public Library of Science (United States), том 10, № 10 DOI
  • 
    • 2015 The systematic approach to describing conformational rearrangements in G-quadruplexes
    • Tsvetkov Vladimir, Pozmogova Galina, Varizhuk Anna
    • в журнале Journal of Biomolecular Structure and Dynamics, издательство Adenine Press (United States), с. 1-11 DOI
  • 
    • 2014 Comparison of the 'chemical' and 'structural' approaches to the optimization of the thrombin-binding aptamer
    • Tatarinova Olga, Tsvetkov Vladimir, Basmanov Dmitry, Barinov Nikolay, Smirnov Igor, Timofeev Edward, Kaluzhny Dmitry, Chuvilin Andrey, Klinov Dmitry, Varizhuk Anna, Pozmogova Galina
    • в журнале PLoS ONE, издательство Public Library of Science (United States), том 9, № 2, с. e89383 DOI
  • 
    • 2013 Synthesis of Triazole-Linked Oligonucleotides with High Affinity to DNA Complements and an Analysis of Their Compatibility with Biosystems
    • Varizhuk Anna M., Kaluzhny Dmitry N., Novikov Roman A., Chizhov Alexandr O., Smirnov Igor P., Chuvilin Andrey N., Tatarinova Olga N., Fisunov Gleb Y., Pozmogova Galina E., Florentiev Vladimir L.
    • в журнале Journal of Organic Chemistry, издательство American Chemical Society (United States), том 78, № 12, с. 5964-5969 DOI
  • 
    • 2013 Synthesis, characterization and in vitro activity of thrombin-binding DNA aptamers with triazole internucleotide linkages
    • Varizhuk Anna M., Tsvetkov Vladimir B., Tatarinova Olga N., Kaluzhny Dmitry N., Florentiev Vladimir L., Timofeev Edward N., Shchyolkina Anna K., Borisova Olga F., Smirnov Igor P., Grokhovsky Sergei L., Aseychev Anton V., Pozmogova Galina E.
    • в журнале European Journal of Medicinal Chemistry, издательство Elsevier BV (Netherlands), том 67, с. 90-97 DOI

• Статьи в сборниках

  • 
    • 2019 Oligonucleotide Primers with G8AE-Clamp Modifications for RT-qPCR Detection of the Low-Copy dsRNA
    • Zatsepin Timofei S., Varizhuk Anna M., Dedkov Vladimir G., Shipulin German A., Aralov Andrey V.
    • в сборнике Methods in Molecular Biology, место издания Springer Berlin Heidelberg, том 1973, с. 281-297 DOI

• Доклады на конференциях

  • • 2018 Ratiometric Green Fluorescent Genetically Encoded Calcium Indicator Based on Ca2+-binding Domains from Fungi. (Стендовый)
    • Авторы: Bogorodskiy A.O., Borshchevskiy V.I., Varizhuk A.M., Pozmogova G.E., Boyden E.S., Anokhin K.V., Enikolopov G.N., Subach F.V., Smirnov I.V., Malyshev A.Y., Jung E.E., Piatkevich K.D., Barykina N.V., Subach O.M.
    • 11th FENS Forum of Neuroscience, Берлин, Германия, 7-12 июля 2018