Гладышев Вадим Николаевич
пользователь
кандидат химических наук с 1992 года
профессор по специальности № медицина с 1 июля 2004 г.
Прежние места работы (Нажмите для отображения)
Professor Brigham & Women’s Hospital, Harvard Medical School
Количество цитирований статей в журналах по данным
Web of Science: 24448,
Scopus: 25962
IstinaResearcherID (IRID): 32725754
Деятельность
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Статьи в журналах
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2022
In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan
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Ribeiro Rui,
Macedo Joana C.,
Costa Madalena,
Ustiyan Vladimir,
Shindyapina Anastasia V.,
Tyshkovskiy Alexander,
Gomes Rita N.,
Castro José Pedro,
Kalin Tanya V.,
Vasques-Nóvoa Francisco,
Nascimento Diana S.,
Dmitriev Sergey E.,
Gladyshev Vadim N.,
Kalinichenko Vladimir V.,
Logarinho Elsa
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в журнале Nature Aging, издательство Springer Nature (Switzerland), том 2, № 5, с. 397-411
DOI
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2021
A standard knockout procedure alters expression of adjacent loci at the translational level
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Egorov Artyom A.,
Alexandrov Alexander I.,
Urakov Valery N.,
Makeeva Desislava S.,
Edakin Roman O.,
Kushchenko Artem S.,
Gladyshev Vadim N.,
Kulakovskiy Ivan V.,
Dmitriev Sergey E.
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в журнале Nucleic Acids Research, издательство Oxford University Press (United Kingdom), том 49, № 19, с. 11134-11144
DOI
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2021
Evolution of natural lifespan variation and molecular strategies of extended lifespan
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Kaya Alaattin,
Phua Cheryl Zi Jin,
Lee Mitchell,
Wang Lu,
Tyshkovskiy Alexander,
Ma Siming,
Barre Benjamin,
Liu Weiqiang,
Harrison Benjamin R.,
Zhao Xiaqing,
Zhou Xuming,
Wasko Brian M.,
Bammler Theo K.,
Promislow Daniel EL,
Kaeberlein Matt,
Gladyshev Vadim N.
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в журнале eLife, том 10
DOI
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2020
CTELS: A Cell-Free System for the Analysis of Translation Termination Rate
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Lashkevich Kseniya A.,
Shlyk Valeriya I.,
Kushchenko Artem S.,
Gladyshev Vadim N.,
Alkalaeva Elena Z.,
Dmitriev Sergey E.
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в журнале Biomolecules, издательство MDPI (Basel, Switzerland), том 10, № 6, с. 911
DOI
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2020
In vivo RNAi mediated eIF3m knockdown is associated with alterations in ribosome biogenesis and transcription, but has limited mRNA-specific translational effects
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Smekalova Elena M.,
Gerashchenko Maxim V.,
O’Connor Patrick B.F.,
Whittaker Charles A.,
Kauffman Kevin J.,
Fefilova Anna S.,
Zatsepin Timofei S.,
Bogorad Roman L.,
Baranov Pavel V.,
Langer Robert,
Gladyshev Vadim N.,
Anderson Daniel G.,
Koteliansky Victor
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в журнале Molecular therapy. Nucleic acids, издательство Nature Publishing Group (United Kingdom), том 19, с. 252-266
DOI
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2020
Molecular signatures of aneuploidy-driven adaptive evolution
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Kaya Alaattin,
Mariotti Marco,
Tyshkovskiy Alexander,
Zhou Xuming,
Hulke Michelle L.,
Siming Ma,
Gerashchenko Maxim V.,
Koren Amnon,
Gladyshev Vadim N.
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в журнале Nature communications, издательство Nature Pub. Group (United Kingdom), том 11, № 1
DOI
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2020
Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes
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Gerashchenko Maxim V.,
Nesterchuk Mikhail V.,
Smekalova Elena M.,
Paulo Joao A.,
Kowalski Piotr S.,
Akulich Kseniya A.,
Bogorad Roman,
Dmitriev Sergey E.,
Gygi Steven,
Zatsepin Timofei,
Anderson Daniel G.,
Gladyshev Vadim N.,
Koteliansky Victor E.
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в журнале Scientific reports, издательство Nature Publishing Group (United Kingdom), том 10, № 1
DOI
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2019
Identification and Application of Gene Expression Signatures Associated with Lifespan Extension
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Tyshkovskiy Alexander,
Bozaykut Perinur,
Borodinova Anastasia A.,
Gerashchenko Maxim V.,
Ables Gene P.,
Garratt Michael,
Khaitovich Philipp,
Clish Clary B.,
Miller Richard A.,
Gladyshev Vadim N.
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в журнале Cell Metabolism, издательство Cell Press (United States), том 30, № 3, с. 573-593.e8
DOI
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2019
Latest advances in aging research and drug discovery
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Daniela Bakula,
Andrea Ablasser,
Adriano Aguzzi,
Adam Antebi,
Nir Barzilai,
Martin-Immanuel Bittner,
Martin Borch Jensen,
Calkhoven Cornelis F.,
Danica Chen,
de Grey Aubrey D.N.J,
Feige Jerome N.,
Anastasia Georgievskaya,
Gladyshev Vadim N.,
Tyler Golato,
Gudkov Andrei V.,
Thorsten Hoppe,
Matt Kaeberlein,
Pekka Katajisto,
Kennedy Brian K.,
Unmesh Lal,
Ana Martin-Villalba,
Moskalev Alexey A.,
Ivan Ozerov,
Petr Michael A.,
Reason,
Rubinsztein David C.,
Alexander Tyshkovskiy,
Quentin Vanhaelen,
Alex Zhavoronkov,
Morten Scheibye-Knudsen
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в журнале AGING-US, том 11, № 22, с. 9971-9981
DOI
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2019
Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation
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O’Connell Amy E.,
Gerashchenko Maxim V.,
O’Donohue Marie-Francoise,
Rosen Samantha M.,
Huntzinger Eric,
Gleeson Diane,
Galli Antonella,
Ryder Edward,
Cao Siqi,
Murphy Quinn,
Kazerounian Shideh,
Morton Sarah U.,
Schmitz-Abe Klaus,
Gladyshev Vadim N.,
Gleizes Pierre-Emmanuel,
Séraphin Bertrand,
Agrawal Pankaj B.
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в журнале PLoS Genetics, издательство Public Library of Science (United States), том 15, № 2, с. e1007917
DOI
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2019
Processive Recoding and Metazoan Evolution of Selenoprotein P: Up to 132 UGAs in Molluscs
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Baclaocos Janinah,
Santesmasses Didac,
Mariotti Marco,
Bierła Katarzyna,
Vetick Michael B.,
Lynch Sharon,
McAllen Rob,
Mackrill John J.,
Loughran Gary,
Guigó Roderic,
Szpunar Joanna,
Copeland Paul R.,
Gladyshev Vadim N.,
Atkins John F.
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в журнале Journal of Molecular Biology, издательство Academic Press (United States)
DOI
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2019
Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming
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Yuancheng Lu,
Krishnan Anitha,
Brommer Benedikt,
Tian Xiao,
Meer Margarita,
Vera Daniel L.,
Wang Chen,
Zeng Qiurui,
Doudou Yu,
Bonkowski Michael S.,
Yang Jae-Hyun,
Hoffmann Emma M.,
Zhou Songlin,
Korobkina Ekaterina,
Davidsohn Noah,
Schultz Michael B.,
Chwalek Karolina,
Rajman Luis A.,
Church George M.,
Hochedlinger Konrad,
Gladyshev Vadim N.,
Horvath Steve,
Gregory-Ksander Meredith S.,
Ksander Bruce R.,
Zhigang He,
Sinclair David A.
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в журнале bioRxiv (The preprint server for biology)
DOI
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2018
AMD1 mRNA employs ribosome stalling as a mechanism for molecular memory formation
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Yordanova Martina M.,
Loughran Gary,
Zhdanov Alexander V.,
Mariotti Marco,
Kiniry Stephen J.,
O’Connor Patrick B.F.,
Andreev Dmitry E.,
Tzani Ioanna,
Saffert Paul,
Michel Audrey M.,
Gladyshev Vadim N.,
Papkovsky Dmitry B.,
Atkins John F.,
Baranov Pavel V.
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в журнале Nature, издательство Nature Publishing Group (United Kingdom), том 553, № 7688, с. 356-360
DOI
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2018
Aging and drug discovery. Meeting report
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Bakula Daniela,
Aliper Alexander M.,
Mamoshina Polina,
Petre Michael A.,
Teklu Amanuel,
Baur Joseph A.,
Campisi Judith,
Ewald Colin Y.,
Georgievskaya Anastasia,
Gladyshev Vadim N.,
Kovalchuk Olga,
Lamming Dudley W.,
Luijsterburg Martijn S.,
Martín-Montalvo Alejandro,
Maudsley Stuart,
Mkrtchyan Garik V.,
Moskalev Alexey,
Jay Olshansky S.,
Ozerov Ivan V.,
Pickett Alexander,
Ristow Michael,
Zhavoronkov Alex,
Scheibye-Knudsen Morten
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в журнале Meeting report, том 10, № 11, с. 3079-3088
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2018
Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity
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Siming Ma,
Avanesov Andrei S.,
Porter Emily,
Lee Byung Cheon,
Mariotti Marco,
Zemskaya Nadezhda,
Guigo Roderic,
Moskalev Alexey A.,
Gladyshev Vadim N.
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в журнале Aging Cell, издательство Blackwell Publishing Inc. (United Kingdom), том 17, № 4, с. e12740
DOI
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2018
Expression of the methionine sulfoxide reductase lost during evolution extends Drosophila lifespan in a methionine-dependent manner
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Lee Byung Cheon,
Lee Hae Min,
Kim Sorah,
Avanesov Andrei S.,
Lee Aro,
Chun Bok-Hwan,
Vorbruggen Gerd,
Gladyshev Vadim N.
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в журнале Scientific reports, издательство Nature Publishing Group (United Kingdom), том 8, № 1, с. 1-11
DOI
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2018
Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity
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Zhang Yichong,
Lee Ji-Hoon,
Paull Tanya T.,
Gehrke Sarah,
D’Alessandro Angelo,
Dou Qianhui,
Gladyshev Vadim N.,
Schroeder Elizabeth A.,
Steyl Samantha K.,
Christian Brooke E.,
Shadel Gerald S.
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в журнале Science signaling, издательство American Association for the Advancement of Science (United States), том 11, № 538, с. eaaq0702
DOI
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2018
Molecular Footprints of Aquatic Adaptation Including Bone Mass Changes in Cetaceans
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Zhou Xuming,
Sun Di,
Guang Xuanmin,
Siming Ma,
Fang Xiaodong,
Mariotti Marco,
Nielsen Rasmus,
Gladyshev Vadim N.,
Yang Guang
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в журнале Genome biology and evolution, издательство Oxford University Press (United Kingdom), том 10, № 3, с. 967-975
DOI
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2018
NEDD9 targetsCOL3A1to promote endothelial fibrosis and pulmonary arterial hypertension
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Samokhin Andriy O.,
Stephens Thomas,
Wertheim Bradley M.,
Wang Rui-Sheng,
Vargas Sara O.,
Yung Lai-Ming,
Cao Minwei,
Brown Marcel,
Arons Elena,
Dieffenbach Paul B.,
Fewell Jason G.,
Matar Majed,
Bowman Frederick P.,
Haley Kathleen J.,
Alba George A.,
Marino Stefano M.,
Kumar Rahul,
Rosas Ivan O.,
Waxman Aaron B.,
Oldham William M.,
Khanna Dinesh,
Graham Brian B.,
Seo Sachiko,
Gladyshev Vadim N.,
Yu Paul B.,
Fredenburgh Laura E.,
Loscalzo Joseph,
Leopold Jane A.,
Maron Bradley A.
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в журнале Science Translational Medicine, издательство American Association for the Advancement of Science (United States), том 10, № 445, с. eaap7294
DOI
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2018
Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence
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Zhao Yang,
Tyshkovskiy Alexander,
Muñoz-Espín Daniel,
Tian Xiao,
Serrano Manuel,
de Magalhaes Joao Pedro,
Nevo Eviatar,
Gladyshev Vadim N.,
Seluanov Andrei,
Gorbunova Vera
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в журнале Proceedings of the National Academy of Sciences of the United States of America, издательство National Academy of Sciences (United States), том 115, № 8, с. 1801-1806
DOI
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2018
Population genomics of finless porpoises reveal an incipient cetacean species adapted to freshwater
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Zhou Xuming,
Guang Xuanmin,
Sun Di,
Shixia Xu,
Mingzhou Li,
Seim Inge,
Jie Wencai,
Yang Linfeng,
Zhu Qianhua,
Jiabao Xu,
Gao Qiang,
Kaya Alaattin,
Dou Qianhui,
Chen Bingyao,
Ren Wenhua,
Shuaicheng Li,
Zhou Kaiya,
Gladyshev Vadim N.,
Nielsen Rasmus,
Fang Xiaodong,
Yang Guang
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в журнале Nature communications, издательство Nature Pub. Group (United Kingdom), том 9, № 1
DOI
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2018
Role of Selenof as a Gatekeeper of Secreted Disulfide-Rich Glycoproteins
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Yim Sun Hee,
Everley Robert A.,
Schildberg Frank A.,
Lee Sang-Goo,
Orsi Andrea,
Barbati Zachary R.,
Karatepe Kutay,
Fomenko Dmitry E.,
Tsuji Petra A.,
Luo Hongbo R.,
Gygi Steven P.,
Sitia Roberto,
Sharpe Arlene H.,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Cell reports, издательство Cell Press (United States), том 23, № 5, с. 1387-1398
DOI
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2018
Selenophosphate synthetase 1 and its role in redox homeostasis, defense and proliferation
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Jiwoon Na,
Jung Jisu,
Bang Jeyoung,
Qiao Lu,
Carlson Bradley A.,
Guo Xiong,
Gladyshev Vadim N.,
Kim Jinhong,
Hatfield Dolph L.,
Lee Byeong Jae
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в журнале Free Radical Biology and Medicine, издательство Elsevier BV (Netherlands), том 18
DOI
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2017
A review of the biomedical innovations for healthy longevity
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Moskalev A.,
Anisimov V.,
Aliper A.,
Artemov A.,
Asadullah K.,
Belsky D.,
Baranova A.,
de Grey A.,
Dixit V.D.,
Debonneuil E.,
Dobrovolskaya E.,
Fedichev P.,
Fedintsev A.,
Fraifeld V.,
Franceschi C.,
Freer R.,
Fulop T.,
Feige J.,
Gems D.,
Gladyshev V.,
Gorbunova V.,
Irincheeva I.,
Jager S.,
Jazwinski S.M.,
Kaeberlein M.,
Kennedy B.,
Khaltourina D.,
Kovalchuk I.,
Kovalchuk O.,
Kozin S.,
Kulminski A.,
Lashmanova E.,
Lezhnina K.,
Liu G.H.,
Longo V.,
Mamoshina P.,
Maslov A.,
Pedro de Magalhaes J.,
Mitchell J.,
Mitnitski A.,
Nikolsky Y.,
Ozerov I.,
Pasyukova E.,
Peregudova D.,
Popov V.,
Proshkina E.,
Putin E.,
Rogaev E.,
Rogina B.,
Schastnaya J.,
Seluanov A.,
Shaposhnikov M.,
Simm A.,
Skulachev V.,
Skulachev M.,
Solovev I.,
Spindler S.,
Stefanova N.,
Suh Y.,
Swick A.,
Tower J.,
Gudkov A.V.,
Vijg J.,
Voronkov A.,
West M.,
Wagner W.,
Yashin A.,
Zemskaya N.,
Zhumadilov Z.,
Zhavoronkov A.
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в журнале AGING-US, том 9, № 1, с. 7-25
DOI
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2017
Age-associated molecular changes are deleterious and may modulate life span through diet
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Lee Sang-Goo,
Kaya Alaattin,
Avanesov Andrei S.,
Podolskiy Dmitriy I.,
Song Eun Ju,
Du-Min Go,
Jin Gwi-Deuk,
Hwang Jae Yeon,
Kim Eun Bae,
Kim Dae-Yong,
Gladyshev Vadim N.
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в журнале Science Advances, том 3, № 2, с. 1601833
DOI
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2017
Aminoglycoside-driven biosynthesis of selenium-deficient Selenoprotein P
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Renko Kostja,
Martitz Janine,
Hybsier Sandra,
Heynisch Bjoern,
Voss Linn,
Everley Robert A.,
Gygi Steven P.,
Stoedter Mette,
Wisniewska Monika,
Köhrle Josef,
Gladyshev Vadim N.,
Schomburg Lutz
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в журнале Scientific reports, издательство Nature Publishing Group (United Kingdom), том 7, № 1
DOI
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2017
Comparative transcriptomics of 5 high-altitude vertebrates and their low-altitude relatives
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Tang Qianzi,
Yiren Gu,
Zhou Xuming,
Jin Long,
Guan Jiuqiang,
Liu Rui,
Jing Li,
Long Kereng,
Tian Shilin,
Che Tiandong,
Silu Hu,
Liang Yan,
Yang Xuemei,
Tao Xuan,
Zhong Zhijun,
Wang Guosong,
Chen Xiaohui,
Diyan Li,
Jideng Ma,
Wang Xun,
Mai Miaomiao,
Jiang An’an,
Luo Xiaolin,
Xuebin Lv,
Gladyshev Vadim N.,
Xuewei Li,
Mingzhou Li
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в журнале GIGASCIENCE, том 6, № 12, с. 1-9
DOI
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2017
Comparison of the redox chemistry of sulfur- and selenium-containing analogs of uracil
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Connor Payne N.,
Geissler Andrew,
Button Aileen,
Sasuclark Alexandru R.,
Schroll Alayne L.,
Ruggles Erik L.,
Gladyshev Vadim N.,
Hondal Robert J.
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в журнале Free Radical Biology and Medicine, издательство Elsevier BV (Netherlands), том 104, с. 249-261
DOI
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2017
Naked Mole Rat Induced Pluripotent Stem Cells and Their Contribution to Interspecific Chimera
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Lee Sang-Goo,
Mikhalchenko Aleksei E.,
Yim Sun Hee,
Lobanov Alexei V.,
Park Jin-Kyu,
Choi Kwang-Hwan,
Bronson Roderick T.,
Lee Chang-Kyu,
Park Thomas J.,
Gladyshev Vadim N.
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в журнале STEM CELL REPORTS, том 9, № 5, с. 1706-1720
DOI
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2017
Selenoprotein MsrB1 promotes anti-inflammatory cytokine gene expression in macrophages and controls immune response in vivo
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Lee Byung Cheon,
Lee Sang-Goo,
Choo Min-Kyung,
Hyung Kim Ji,
Lee Hae Min,
Kim Sorah,
Fomenko Dmitri E.,
Kim Hwa-Young,
Park Jin Mo,
Gladyshev Vadim N.
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в журнале Scientific reports, издательство Nature Publishing Group (United Kingdom), том 7, № 1
DOI
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2017
The Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I)
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Salinas Gustavo,
Gao Wei,
Wang Yang,
Bonilla Mariana,
Long Yu,
Novikov Andrey,
Virginio Veridiana G.,
Ferreira Henrique B.,
Vieites Marisol,
Gladyshev Vadim N.,
Gambino Dinorah,
Dai Shaodong
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в журнале Antioxidants and Redox Signaling, издательство Mary Ann Liebert Inc. (United States), том 27, № 18, с. 1491-1504
DOI
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2017
Translation fidelity coevolves with longevity
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Zhonghe Ke,
Mallik Pramit,
Johnson Adam B.,
Luna Facundo,
Nevo Eviatar,
Zhang Zhengdong D.,
Gladyshev Vadim N.,
Seluanov Andrei,
Gorbunova Vera
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в журнале Aging Cell, издательство Blackwell Publishing Inc. (United Kingdom), том 16, № 5, с. 988-993
DOI
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2016
Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity
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Siming Ma,
Akhil Upneja,
Andrzej Galecki,
Yi-Miau Tsai,
Burant Charles F.,
Sasha Raskind,
Quanwei Zhang,
Zhang Zhengdong D.,
Andrei Seluanov,
Vera Gorbunova,
Clish Clary B.,
Miller Richard A.,
Gladyshev Vadim N.
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в журнале eLife, № 5, с. 1-25
DOI
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2016
Comprehensive variation discovery and recovery of missing sequence in the pig genome using multiple de novo assemblies
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Mingzhou Li,
Chen Lei,
Tian Shilin,
Lin Yu,
Tang Qianzi,
Zhou Xuming,
Diyan Li,
Yeung Carol K.L.,
Che Tiandong,
Jin Long,
Yuhua Fu,
Jideng Ma,
Wang Xun,
Jiang Anan,
Lan Jing,
Pan Qi,
Liu Yingkai,
Luo Zonggang,
Guo Zongyi,
Liu Haifeng,
Zhu Li,
Shuai Surong,
Tang Guoqing,
Zhao Jiugang,
Jiang Yanzhi,
Bai Lin,
Zhang Shunhua,
Mai Miaomiao,
Changchun Li,
Wang Dawei,
Yiren Gu,
Wang Guosong,
Hongfeng Lu,
Yan Li,
Zhu Haihao,
Zongwen Li,
Ming Li,
Gladyshev Vadim N.,
Jiang Zhi,
Zhao Shuhong,
Wang Jinyong,
Ruiqiang Li,
Xuewei Li
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в журнале Genome Research, издательство Cold Spring Harbor Laboratory Press (United States), том 27, № 5, с. 865-874
DOI
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2016
Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration
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Carlson Bradley A.,
Tobe Ryuta,
Yefremova Elena,
Tsuji Petra A.,
Hoffmann Victoria J.,
Schweizer Ulrich,
Gladyshev Vadim N.,
Hatfield Dolph L.,
Conrad Marcus
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в журнале Redox Biology, том 9, с. 22-31
DOI
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2016
LokiarchaeotaMarks the Transition between the Archaeal and Eukaryotic Selenocysteine Encoding Systems
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Mariotti Marco,
Lobanov Alexei V.,
Manta Bruno,
Santesmasses Didac,
Bofill Andreu,
Guigó Roderic,
Gabaldón Toni,
Gladyshev Vadim N.
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в журнале Molecular Biology and Evolution, издательство Oxford University Press (United Kingdom), том 33, № 9, с. 2441-2453
DOI
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2016
Methionine sulfoxide reductase B1 deficiency does not increase high-fat diet-induced insulin resistance in mice
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Heo Jung-Yoon,
Cha Hye-Na,
Young Kim Ki,
Lee Eujin,
Kim Suk-Jeong,
Kim Yong-Woon,
Kim Jong-Yeon,
Lee In-Kyu,
Gladyshev Vadim N.,
Kim Hwa-Young,
Park So-Young
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в журнале Free Radical Research, издательство Taylor & Francis (United Kingdom), том 51, № 1, с. 24-37
DOI
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2016
Population Genomics Reveals Low Genetic Diversity and Adaptation to Hypoxia in Snub-Nosed Monkeys
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Zhou Xuming,
Meng Xuehong,
Liu Zhijin,
Chang Jiang,
Wang Boshi,
Mingzhou Li,
Wengel Pablo Orozco-ter,
Tian Shilin,
Wen Changlong,
Wang Ziming,
Garber Paul A.,
Pan Huijuan,
Xinping Ye,
Xiang Zuofu,
Bruford Michael W.,
Edwards Scott V.,
Cao Yinchuan,
Shuancang Yu,
Gao Lianju,
Cao Zhisheng,
Liu Guangjian,
Ren Baoping,
Shi Fanglei,
Peterfi Zalan,
Dayong Li,
Baoguo Li,
Jiang Zhi,
Junsheng Li,
Gladyshev Vadim N.,
Ruiqiang Li,
Ming Li
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в журнале Molecular Biology and Evolution, издательство Oxford University Press (United Kingdom), том 33, № 10, с. 2670-2681
DOI
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2016
Position-dependent termination and widespread obligatory frameshifting in Euplotes translation
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Lobanov Alexei V.,
Heaphy Stephen M.,
Turanov Anton A.,
Gerashchenko Maxim V.,
Pucciarelli Sandra,
Devaraj Raghul R.,
Xie Fang,
Petyuk Vladislav A.,
Smith Richard D.,
Klobutcher Lawrence A.,
Atkins John F.,
Miceli Cristina,
Hatfield Dolph L.,
Baranov Pavel V.,
Gladyshev Vadim N.
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в журнале Nature Structural and Molecular Biology, издательство Nature Publishing Group (United Kingdom), том 24, № 1, с. 61-68
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2016
Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals
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Tobe R.,
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Huh J.H.,
Castro N.P.,
Xu X.M.,
Tsuji P.A.,
Lee S.G.,
Bang J.,
Na J.W.,
Kong Y.Y.,
Beaglehole D.,
Southon E.,
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Tessarollo L.,
Salomon D.S.,
Schweizer U.,
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в журнале Biochemical Journal, издательство Portland Press, Ltd. (United Kingdom), том 473, № 14, с. 2141-2154
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2016
Selenoprotein Gene Nomenclature
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Gladyshev Vadim N.,
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Berry Marla J.,
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Bruford Elspeth A.,
Burk Raymond F.,
Carlson Bradley A.,
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Hatfield Dolph L.,
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Holmgren Arne,
Hondal Robert J.,
Howard Michael T.,
Huang Kaixun,
Kim Hwa-Young,
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Köhrle Josef,
Krol Alain,
Kryukov Gregory V.,
Lee Byeong Jae,
Lee Byung Cheon,
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Lobanov Alexei V.,
Loscalzo Joseph,
Maiorino Matilde,
Mariotti Marco,
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Rayman Margaret P.,
Rozovsky Sharon,
Salinas Gustavo,
Schmidt Edward E.,
Schomburg Lutz,
Schweizer Ulrich,
Simonović Miljan,
Sunde Roger A.,
Tsuji Petra A.,
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Zhang Yan
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 291, № 46, с. 24036-24040
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2016
Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis
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Cox Andrew G.,
Tsomides Allison,
Kim Andrew J.,
Saunders Diane,
Hwang Katie L.,
Evason Kimberley J.,
Heidel Jerry,
Brown Kristin K.,
Yuan Min,
Lien Evan C.,
Lee Byung Cheon,
Nissim Sahar,
Dickinson Bryan,
Chhangawala Sagar,
Chang Christopher J.,
Asara John M.,
Houvras Yariv,
Gladyshev Vadim N.,
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в журнале Proceedings of the National Academy of Sciences of the United States of America, издательство National Academy of Sciences (United States), том 113, № 38, с. 5562
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2015
Cell Proliferation and Motility Are Inhibited by G1 Phase Arrest in 15-kDa Selenoprotein-Deficient Chang Liver Cells
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Jeyoung Bang,
Jang Hoe Huh,
Ji-Woon Na,
Qiao Lu,
Carlson Bradley A.,
Ryuta Tobe,
Tsuji Petra A.,
Gladyshev Vadim N.,
Hatfield Dolph L.,
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в журнале Molecules and Cells, издательство Springer Verlag (Germany), том 38, № 5, с. 457-465
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2015
Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human
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MacRae Sheila L.,
Zhang Quanwei,
Lemetre Christophe,
Seim Inge,
Calder Robert B.,
Hoeijmakers Jan,
Suh Yousin,
Gladyshev Vadim N.,
Seluanov Andrei,
Gorbunova Vera,
Vijg Jan,
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в журнале Aging Cell, издательство Blackwell Publishing Inc. (United Kingdom), том 14, № 2, с. 288-291
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2015
DNA repair in species with extreme lifespan differences
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MacRae Sheila L.,
Croken Matthew McKnight,
Calder R.B.,
Aliper Alexander,
Milholland Brandon,
White Ryan R.,
Zhavoronkov Alexander,
Gladyshev Vadim N.,
Seluanov Andrei,
Gorbunova Vera,
Zhang Zhengdong D.,
Vijg Jan
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в журнале AGING-US, том 7, № 12, с. 1171-1182
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2015
Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway
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Bang Jeyoung,
Jang Mihyun,
Huh Jang Hoe,
Ji-Woon Na,
Shim Myoungsup,
Carlson Bradley A.,
Tobe Ryuta,
Tsuji Petra A.,
Gladyshev Vadim N.,
Hatfield Dolph L.,
Lee Byeong Jae
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в журнале Biochemical and Biophysical Research Communications, издательство Academic Press (United States), том 456, № 4, с. 884-890
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2015
Endogenous hydrogen sulfide production is essential for dietary restriction benefits
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Hine C.,
Harputlugil E.,
Zhang Y.,
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Lee B.C.,
Brace L.,
Longchamp A.,
Treviño-Villarreal J.H.,
Mejia P.,
Ozaki C.K.,
Wang R.,
Gladyshev V.N.,
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в журнале Cell, издательство Cell Press (United States), том 160, № 1-2, с. 132-144
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2015
Evolution of selenophosphate synthetases: Emergence and relocation of function through independent duplications and recurrent subfunctionalization
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Mariotti M.,
Santesmasses D.,
Capella-Gutierrez S.,
Mateo A.,
Arnan C.,
Johnson R.,
D’Aniello S.,
Yim S.H.,
Gladyshev V.N.,
Serras F.,
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в журнале Genome Research, издательство Cold Spring Harbor Laboratory Press (United States), том 25, № 9, с. 1256-1267
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2015
Gene expression defines natural changes in mammalian lifespan
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Fushan Alexey A.,
Turanov Anton A.,
Lee Sang-Goo,
Kim Eun Bae,
Lobanov Alexei V.,
Yim Sun Hee,
Buffenstein Rochelle,
Lee Sang-Rae,
Chang Kyu-Tae,
Rhee Hwanseok,
Kim Jong-So,
Yang Kap-Seok,
Gladyshev Vadim N.
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в журнале Aging Cell, издательство Blackwell Publishing Inc. (United Kingdom), том 14, № 3, с. 352-365
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2015
INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform
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Tian X.,
Azpurua J.,
Ke Z.,
Augereau A.,
Zhang Z.D.,
Vijg J.,
Gladyshev V.N.,
Gorbunova V.,
Seluanov A.
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в журнале Proceedings of the National Academy of Sciences of the United States of America, издательство National Academy of Sciences (United States), том 112, № 4, с. 1053-1058
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2015
Mechanism-based Proteomic Screening Identifies Targets of Thioredoxin-like Proteins
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Nakao Lia S.,
Everley Robert A.,
Marino Stefano M.,
Lo Sze M.,
de Souza Luiz E.,
Gygi Steven P.,
Gladyshev Vadim N.
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 290, № 9, с. 5685-5695
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2015
Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity
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Ma S.,
Lee S.G.,
Kim E.B.,
Park T.J.,
Seluanov A.,
Gorbunova V.,
Buffenstein R.,
Seravalli J.,
Gladyshev V.N.
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в журнале Cell reports, издательство Cell Press (United States), том 13, № 7, с. 1319-1326
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2015
Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine
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Turanov Anton A.,
Everley Robert A.,
Hybsier Sandra,
Renko Kostja,
Schomburg Lutz,
Gygi Steven P.,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале PLoS ONE, издательство Public Library of Science (United States), том 10, № 10, с. e0140353
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2015
Site-Specific Proteomic Mapping Identifies Selectively Modified Regulatory Cysteine Residues in Functionally Distinct Protein Networks
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Gould Neal S.,
Evans Perry,
Martínez-Acedo Pablo,
Marino Stefano M.,
Gladyshev Vadim N.,
Carroll Kate S.,
Ischiropoulos Harry
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в журнале Chemistry and Biology, издательство Cell Press (United States), том 22, № 7, с. 965-975
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2015
The 15kDa Selenoprotein and Thioredoxin Reductase 1 Promote Colon Cancer by Different Pathways
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Tsuji Petra A.,
Carlson Bradley A.,
Yoo Min-Hyuk,
Naranjo-Suarez Salvador,
Xue-Ming Xu,
Yiwen He,
Asaki Esther,
Seifried Harold E.,
Reinhold William C.,
Davis Cindy D.,
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в журнале PLoS ONE, издательство Public Library of Science (United States), том 10, № 4, с. e0124487
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2014
Adaptations to a Subterranean Environment and Longevity Revealed by the Analysis of Mole Rat Genomes
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Fang Xiaodong,
Seim Inge,
Huang Zhiyong,
Gerashchenko Maxim V.,
Xiong Zhiqiang,
Turanov Anton A.,
Zhu Yabing,
Lobanov Alexei V.,
Fan Dingding,
Yim Sun Hee,
Yao Xiaoming,
Siming Ma,
Yang Lan,
Lee Sang-Goo,
Kim Eun Bae,
Bronson Roderick T.,
Šumbera Radim,
Buffenstein Rochelle,
Zhou Xin,
Krogh Anders,
Park Thomas J.,
Zhang Guojie,
Wang Jun,
Gladyshev Vadim N.
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в журнале Cell reports, издательство Cell Press (United States), том 8, № 5, с. 1354-1364
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2014
Adjustments, extinction, and remains of selenocysteine incorporation machinery in the nematode lineage
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Otero L.,
Romanelli-Cedrez L.,
Turanov A.A.,
Gladyshev V.N.,
Miranda-Vizuete A.,
Salinas G.
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в журнале RNA, том 20, № 7, с. 1023-1034
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2014
Genome-wide RNAi ionomics screen reveals new genes and regulation of human trace element metabolism
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Malinouski Mikalai,
Hasan Nesrin M.,
Zhang Yan,
Seravalli Javier,
Lin Jie,
Avanesov Andrei,
Lutsenko Svetlana,
Gladyshev Vadim N.
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в журнале Nature communications, издательство Nature Pub. Group (United Kingdom), том 5, № 1
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2014
Genome-wide association study of selenium concentrations
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Cornelis Marilyn C.,
Fornage Myriam,
Foy Millennia,
Xun Pengcheng,
Gladyshev Vadim N.,
Morris Steve,
Chasman Daniel I.,
Hu Frank B.,
Rimm Eric B.,
Kraft Peter,
Jordan Joanne M.,
Mozaffarian Dariush,
He Ka
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в журнале Human Molecular Genetics, издательство Oxford University Press (United Kingdom), том 24, № 5, с. 1469-1477
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2014
Inhibition of Cellular Methyltransferases Promotes Endothelial Cell Activation by Suppressing Glutathione Peroxidase 1 Protein Expression
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Barroso Madalena,
Florindo Cristina,
Kalwa Hermann,
Silva Zélia,
Turanov Anton A.,
Carlson Bradley A.,
de Almeida Isabel Tavares,
Blom Henk J.,
Gladyshev Vadim N.,
Hatfield Dolph L.,
Michel Thomas,
Castro Rita,
Loscalzo Joseph,
Handy Diane E.
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 289, № 22, с. 15350-15362
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2014
Intrinsic Expression of a Multiexon Type 3 Deiodinase Gene Controls Zebrafish Embryo Size
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Guo Cuicui,
Chen Xia,
Song Huaidong,
Maynard Michelle A.,
Zhou Yi,
Lobanov Alexei V.,
Gladyshev Vadim N.,
Ganis Jared J.,
Wiley David,
Jugo Rebecca H.,
Lee Nicholas Y.,
Castroneves Luciana A.,
Zon Leonard I.,
Scanlan Thomas S.,
Feldman Henry A.,
Huang Stephen A.
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в журнале Endocrinology, издательство The Endocrine Society (United States), том 155, № 10, с. 4069-4080
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2014
Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino-acid status
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Lee Byung Cheon,
Kaya Alaattin,
Siming Ma,
Kim Gwansu,
Gerashchenko Maxim V.,
Yim Sun Hee,
Zhen Hu,
Harshman Lawrence G.,
Gladyshev Vadim N.
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в журнале Nature communications, издательство Nature Pub. Group (United Kingdom), том 5
DOI
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2014
Selenoprotein S is involved in maintenance and transport of multiprotein complexes
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Turanov Anton A.,
Shchedrina Valentina A.,
Everley Robert A.,
Lobanov Alexei V.,
Yim Sun Hee,
Marino Stefano M.,
Gygi Steven P.,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Biochemical Journal, издательство Portland Press, Ltd. (United Kingdom), том 462, № 3, с. 555-565
DOI
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2014
The First International Mini-Symposium on Methionine Restriction and Lifespan
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Ables Gene P.,
Brown-Borg Holly M.,
Buffenstein Rochelle,
Church Christopher D.,
Elshorbagy Amany K.,
Gladyshev Vadim N.,
Huang Tsang-hai,
Miller Richard A.,
Mitchell James R.,
Richie John P.,
Rogina Blanka,
Stipanuk Martha H.,
Orentreich David S.,
Orentreich Norman
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в журнале Frontiers in genetics, издательство Frontiers Research Foundation. (Lausanne, Switzerland), том 5
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2014
The transcriptome of the bowhead whale $\less$i$\greater$Balaena mysticetus$\less$/i$\greater$ reveals adaptations of the longest-lived mammal
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Seim Inge,
Siming Ma,
Zhou Xuming,
Gerashchenko Maxim V.,
Lee Sang-Goo,
Suydam Robert,
George John C.,
Bickham John W.,
Gladyshev Vadim N.
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в журнале AGING-US, том 6, № 10, с. 879-899
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2014
Thiol Peroxidase Deficiency Leads to Increased Mutational Load and Decreased Fitness in Saccharomyces cerevisiae
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Kaya A.,
Lobanov A.V.,
Gerashchenko M.V.,
Koren A.,
Fomenko D.E.,
Koc A.,
Gladyshev V.N.
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в журнале Genetics, издательство Genetics Society of America (United States), том 198, № 3, с. 905-917
DOI
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2013
Contrasting roles of dietary selenium and selenoproteins in chemically induced hepatocarcinogenesis
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Kasaikina M.V.,
Turanov A.A.,
Avanesov A.,
Schweizer U.,
Seeher S.,
Bronson R.T.,
Novoselov S.N.,
Carlson B.A.,
Hatfield D.L.,
Gladyshev V.N.
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в журнале Carcinogenesis, издательство Oxford University Press (United Kingdom), том 34, № 5, с. 1089-1095
DOI
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2013
Diversity of Plant Methionine Sulfoxide Reductases B and Evolution of a Form Specific for Free Methionine Sulfoxide
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Tien Le Dung,
Tarrago Lionel,
Watanabe Yasuko,
Kaya Alaattin,
Lee Byung Cheon,
Tran Uyen,
Nishiyama Rie,
Fomenko Dmitri E.,
Gladyshev Vadim N.,
Tran Lam-Son Phan
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в журнале PLoS ONE, издательство Public Library of Science (United States), том 8, № 6, с. e65637
DOI
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2013
High Error Rates in Selenocysteine Insertion in Mammalian Cells Treated with the Antibiotic Doxycycline, Chloramphenicol, or Geneticin
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Tobe Ryuta,
Naranjo-Suarez Salvador,
Everley Robert A.,
Carlson Bradley A.,
Turanov Anton A.,
Tsuji Petra A.,
Yoo Min-Hyuk,
Gygi Steven P.,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 288, № 21, с. 14709-14715
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2013
MsrB1 and MICALs Regulate Actin Assembly and Macrophage Function via Reversible Stereoselective Methionine Oxidation
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Lee B.,
Péterfi Z.,
Hoffmann F.W.,
Moore R.E.,
Kaya A.,
Avanesov A.,
Tarrago L.,
Zhou Y.,
Weerapana E.,
Fomenko D.E.,
Hoffmann P.R.,
Gladyshev V.N.
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в журнале Molecular Cell, издательство Cell Press (United States), том 51, № 3, с. 397-404
DOI
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2013
Regulation of HIF-1$\upalpha$ activity by overexpression of thioredoxin is independent of thioredoxin reductase status
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Naranjo-Suarez Salvador,
Carlson Bradley A.,
Tobe Ryuta,
Yoo Min-Hyuk,
Tsuji Petra A.,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале Molecules and Cells, издательство Springer Verlag (Germany), том 36, № 2, с. 151-157
DOI
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2013
Selenium and Selenoprotein Deficiencies Induce Widespread Pyogranuloma Formation in Mice, while High Levels of Dietary Selenium Decrease Liver Tumor Size Driven by TGF$\upalpha$
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Moustafa Mohamed E.,
Carlson Bradley A.,
Anver Miriam R.,
Bobe Gerd,
Zhong Nianxin,
Ward Jerrold M.,
Perella Christine M.,
Hoffmann Victoria J.,
Rogers Keith,
Combs Gerald F.,
Schweizer Ulrich,
Merlino Glenn,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале PLoS ONE, издательство Public Library of Science (United States), том 8, № 2, с. e57389
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2013
SelenoDB 2.0: annotation of selenoprotein genes in animals and their genetic diversity in humans
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Romagné Frédéric,
Santesmasses Didac,
White Louise,
Sarangi Gaurab K.,
Mariotti Marco,
Hübler Ron,
Weihmann Antje,
Parra Genís,
Gladyshev Vadim N.,
Guigó Roderic,
Castellano Sergi
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в журнале Nucleic Acids Research, издательство Oxford University Press (United Kingdom), том 42, № D1, с. D437-D443
DOI
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2013
The central role of selenium in the biochemistry and ecology of the harmful pelagophyte, Aureococcus anophagefferens
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Gobler Christopher J.,
Lobanov Alexei V.,
Tang Ying-Zhong,
Turanov Anton A.,
Zhang Yan,
Doblin Martina,
Taylor Gordon T.,
Sañudo-Wilhelmy Sergio A.,
Grigoriev Igor V.,
Gladyshev Vadim N.
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в журнале ISME Journal, издательство Nature Publishing Group (United Kingdom), том 7, № 7, с. 1333-1343
DOI
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2012
Composition and Evolution of the Vertebrate and Mammalian Selenoproteomes
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Mariotti Marco,
Ridge Perry G.,
Zhang Yan,
Lobanov Alexei V.,
Pringle Thomas H.,
Guigo Roderic,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале PLoS ONE, издательство Public Library of Science (United States), том 7, № 3, с. e33066
DOI
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2012
Draft macronuclear genome of a ciliate Euplotes crassus
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Vinogradov D.V.,
Tsoĭ O.V.,
Zaika A.V.,
Lobanov A.V.,
Turanov A.A.,
Gladyshev V.N.,
Gel'fand M.S.
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в журнале Molekuliarnaia biologiia, издательство Russian Academy of Sciences (Russian Federation), том 46, № 2, с. 361-366
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2012
High-Resolution Imaging of Selenium in Kidneys: A Localized Selenium Pool Associated with Glutathione Peroxidase 3
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Malinouski Mikalai,
Kehr Sebastian,
Finney Lydia,
Vogt Stefan,
Carlson Bradley A.,
Seravalli Javier,
Jin Richard,
Handy Diane E.,
Park Thomas J.,
Loscalzo Joseph,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Antioxidants and Redox Signaling, издательство Mary Ann Liebert Inc. (United States), том 16, № 3, с. 185-192
DOI
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2012
Identification of Thioredoxin Glutathione Reductase Inhibitors That Kill Cestode and Trematode Parasites
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Ross Fabiana,
Hernández Paola,
Porcal Williams,
López Gloria V.,
Cerecetto Hugo,
González Mercedes,
Basika Tatiana,
Carmona Carlos,
Fló Martín,
Maggioli Gabriela,
Bonilla Mariana,
Gladyshev Vadim N.,
Boiani Mariana,
Salinas Gustavo
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в журнале PLoS ONE, издательство Public Library of Science (United States), том 7, № 4, с. e35033
DOI
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2012
Thioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanism
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Tobe Ryuta,
Yoo Min-Hyuk,
Fradejas Noelia,
Carlson Bradley A.,
Calvo Soledad,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале Biochemical Journal, издательство Portland Press, Ltd. (United Kingdom), том 445, № 3, с. 423-430
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2012
Thioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis
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Carlson Bradley A.,
Yoo Min-Hyuk,
Tobe Ryuta,
Mueller Charles,
Naranjo-Suarez Salvador,
Hoffmann Victoria J.,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале Carcinogenesis, издательство Oxford University Press (United Kingdom), том 33, № 9, с. 1806-1813
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2011
A 4-Selenocysteine, 2-Selenocysteine Insertion Sequence (SECIS) Element Methionine Sulfoxide Reductase fromMetridium senileReveals a Non-catalytic Function of Selenocysteines
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Lee Byung Cheon,
Lobanov Alexey V.,
Marino Stefano M.,
Kaya Alaattin,
Seravalli Javier,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 286, № 21, с. 18747-18755
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2011
Abstract 1868: Sep15 knockout in mice provides protection against chemically-induced aberrant crypt formation
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Tsuji Petra A.,
Carlson Bradley A.,
Yoo Min-Hyuk,
Xue-Ming Xu,
Naranjo-Suarez Salvador,
Fomenko Dmitri,
Gladyshev Vadim N.,
Hatfield Dolph L.,
Davis Cindy D.
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в журнале Cancer Research, издательство American Association for Cancer Research (United States), том 71, № 8 Supplement, с. 1868-1868
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2011
Analyses of Fruit Flies That Do Not Express Selenoproteins or Express the Mouse Selenoprotein, Methionine Sulfoxide Reductase B1, Reveal a Role of Selenoproteins in Stress Resistance
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Shchedrina Valentina A.,
Kabil Hadise,
Vorbruggen Gerd,
Lee Byung Cheon,
Turanov Anton A.,
Hirosawa-Takamori Mitsuko,
Kim Hwa-Young,
Harshman Lawrence G.,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 286, № 34, с. 29449-29461
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2011
Biosynthesis of Selenocysteine, the 21st Amino Acid in the Genetic Code, and a Novel Pathway for Cysteine Biosynthesis
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Turanov Anton A.,
Xue-Ming Xu,
Carlson Bradley A.,
Yoo Min-Hyuk,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале Advances in Nutrition, том 2, № 2, с. 122-128
DOI
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2011
Dietary selenium affects host selenoproteome expression by influencing the gut microbiota
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Kasaikina Marina V.,
Kravtsova Marina A.,
Lee Byung Cheon,
Seravalli Javier,
Peterson Daniel A.,
Walter Jens,
Legge Ryan,
Benson Andrew K.,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале FASEB Journal, издательство Federation of American Societies for Experimental Biology (United States), том 25, № 7, с. 2492-2499
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2011
Functional Null Mutations of MSRB3 Encoding Methionine Sulfoxide Reductase Are Associated with Human Deafness DFNB74
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Ahmed Zubair M.,
Yousaf Rizwan,
Lee Byung Cheon,
Khan Shaheen N.,
Lee Sue,
Lee Kwanghyuk,
Husnain Tayyab,
Rehman Atteeq Ur,
Bonneux Sarah,
Ansar Muhammad,
Ahmad Wasim,
Leal Suzanne M.,
Gladyshev Vadim N.,
Belyantseva Inna A.,
Camp Guy Van,
Riazuddin Sheikh,
Friedman Thomas B.,
Riazuddin Saima
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в журнале American Journal of Human Genetics, издательство University of Chicago Press (United States), том 88, № 1, с. 19-29
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2011
Genome sequencing reveals insights into physiology and longevity of the naked mole rat
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Kim E.B.,
Fang X.,
Fushan A.A.,
Huang Z.,
Lobanov A.V.,
Han L.,
Marino S.M.,
Sun X.,
Turanov A.A.,
Yang P.,
Yim S.H.,
Zhao X.,
Kasaikina M.V.,
Stoletzki N.,
Peng C.,
Polak P.,
Xiong Z.,
Kiezun A.,
Zhu Y.,
Chen Y.,
Kryukov G.V.,
Zhang Q.,
Peshkin L.,
Yang L.,
Bronson R.T.,
Buffenstein R.,
Wang B.,
Han C.,
Li Q.,
Chen L.,
Zhao W.,
Sunyaev S.R.,
Park T.J.,
Zhang G.,
Wang J.,
Gladyshev V.N.
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в журнале Nature, издательство Nature Publishing Group (United Kingdom), том 479, № 7372, с. 223-227
DOI
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2011
Identification and Characterization of Alternatively Transcribed Form of Peroxiredoxin IV Gene That Is Specifically Expressed in Spermatids of Postpubertal Mouse Testis
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Yim Sun Hee,
Kim Yoo-Jin,
Young Oh Sue,
Fujii Junichi,
Zhang Yan,
Gladyshev Vadim N.,
Rhee Sue Goo
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 286, № 45, с. 39002-39012
DOI
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2011
Inhibition of selenocysteine tRNA[Ser]Sec aminoacylation provides evidence that aminoacylation is required for regulatory methylation of this tRNA
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Kim Jin Young,
Carlson Bradley A.,
Xue-Ming Xu,
Zeng Yu,
Chen Shawn,
Gladyshev Vadim N.,
Lee Byeong Jae,
Hatfield Dolph L.
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в журнале Biochemical and Biophysical Research Communications, издательство Academic Press (United States), том 409, № 4, с. 814-819
DOI
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2011
Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection
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Suzuki Yo,
Onge Robert P.St,
Mani Ramamurthy,
King Oliver D.,
Heilbut Adrian,
Labunskyy Vyacheslav M.,
Chen Weidong,
Pham Linda,
Zhang Lan V.,
Tong Amy H.Y.,
Nislow Corey,
Giaever Guri,
Gladyshev Vadim N.,
Vidal Marc,
Schow Peter,
Lehár Joseph,
Roth Frederick P.
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в журнале Nature Methods, издательство Nature Publishing Group (United Kingdom), том 8, № 2, с. 159-164
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2011
Niche of harmful alga Aureococcus anophagefferens revealed through ecogenomics
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Gobler C.J.,
Berry D.L.,
Dyhrman S.T.,
Wilhelm S.W.,
Salamov A.,
Lobanov A.V.,
Zhang Y.,
Collier J.L.,
Wurch L.L.,
Kustka A.B.,
Dill B.D.,
Shah M.,
VerBerkmoes N.C.,
Kuo A.,
Terry A.,
Pangilinan J.,
Lindquist E.A.,
Lucas S.,
Paulsen I.T.,
Hattenrath-Lehmann T.K.,
Talmage S.C.,
Walker E.A.,
Koch F.,
Burson A.M.,
Marcoval M.A.,
Tang Y.Z.,
LeCleir G.R.,
Coyne K.J.,
Berg G.M.,
Bertrand E.M.,
Saito M.A.,
Gladyshev V.N.,
Grigoriev I.V.
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в журнале Proceedings of the National Academy of Sciences of the United States of America, издательство National Academy of Sciences (United States), том 108, № 11, с. 4352-4357
DOI
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2011
Reduced Utilization of Selenium by Naked Mole Rats Due to a Specific Defect in GPx1 Expression
-
Kasaikina Marina V.,
Lobanov Alexei V.,
Malinouski Mikalai Y.,
Lee Byung Cheon,
Seravalli Javier,
Fomenko Dmitri E.,
Turanov Anton A.,
Finney Lydia,
Vogt Stefan,
Park Thomas J.,
Miller Richard A.,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 286, № 19, с. 17005-17014
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2011
Roles of the 15-kDa Selenoprotein (Sep15) in Redox Homeostasis and Cataract Development Revealed by the Analysis of Sep 15 Knockout Mice
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Kasaikina Marina V.,
Fomenko Dmitri E.,
Labunskyy Vyacheslav M.,
Lachke Salil A.,
Qiu Wenya,
Moncaster Juliet A.,
Zhang Jie,
Wojnarowicz Mark W.,
Natarajan Sathish Kumar,
Malinouski Mikalai,
Schweizer Ulrich,
Tsuji Petra A.,
Carlson Bradley A.,
Maas Richard L.,
Lou Marjorie F.,
Goldstein Lee E.,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 286, № 38, с. 33203-33212
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2011
Tandem use of selenocysteine: adaptation of a selenoprotein glutaredoxin for reduction of selenoprotein methionine sulfoxide reductase
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Kim Moon-Jung,
Lee Byung Cheon,
Jeong Jaeho,
Lee Kong-Joo,
Hwang Kwang Yeon,
Gladyshev Vadim N.,
Kim Hwa-Young
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в журнале Molecular Microbiology, издательство Blackwell Publishing Inc. (United Kingdom), том 79, № 5, с. 1194-1203
DOI
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2011
Thiol peroxidases mediate specific genome-wide regulation of gene expression in response to hydrogen peroxide
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Fomenko D.E.,
Koc A.,
Agisheva N.,
Jacobsen M.,
Kaya A.,
Malinouski M.,
Rutherford J.C.,
Siu K.L.,
Jin D.Y.,
Winge D.R.,
Gladyshev V.N.
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в журнале Proceedings of the National Academy of Sciences of the United States of America, издательство National Academy of Sciences (United States), том 108, № 7, с. 2729-2734
DOI
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2011
Thioredoxin 1-Mediated Post-Translational Modifications: Reduction, Transnitrosylation, Denitrosylation, and Related Proteomics Methodologies
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Changgong Wu,
Parrott Andrew M.,
Cexiong Fu,
Liu Tong,
Marino Stefano M.,
Gladyshev Vadim N.,
Jain Mohit R.,
Baykal Ahmet T.,
Qing Li,
Oka Shinichi,
Sadoshima Junichi,
Beuve Annie,
Simmons William J.,
Hong Li
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в журнале Antioxidants and Redox Signaling, издательство Mary Ann Liebert Inc. (United States), том 15, № 9, с. 2565-2604
DOI
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2011
Use of environmental scanning electron microscopy for in situ observation of interaction of cells with micro- and nanoprobes
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Goponenko A.V.,
Boyle B.J.,
Jahan K.I.,
Gerashchenko M.V.,
Fomenko D.E.,
Gladyshev V.N.,
Dzenis Y.A.
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в журнале Micro & nano letters, издательство Institution of Engineering and Technology (United Kingdom), том 6, № 8, с. 603
DOI
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2010
Compartmentalization and Regulation of Mitochondrial Function by Methionine Sulfoxide Reductases in Yeast
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Kaya Alaattin,
Koc Ahmet,
Lee Byung Cheon,
Fomenko Dmitri E.,
Rederstorff Mathieu,
Krol Alain,
Lescure Alain,
Gladyshev Vadim N.
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в журнале Biochemistry, издательство American Chemical Society (United States), том 49, № 39, с. 8618-8625
DOI
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2010
Deficiency in the 15-kDa Selenoprotein Inhibits Tumorigenicity and Metastasis of Colon Cancer Cells
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Irons R.,
Tsuji P.A.,
Carlson B.A.,
Ouyang P.,
Yoo M.H.,
Xu X.M.,
Hatfield D.L.,
Gladyshev V.N.,
Davis C.D.
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в журнале Cancer Prevention Research, том 3, № 5, с. 630-639
DOI
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2010
Delineating the Role of Glutathione Peroxidase 4 in Protecting Cells Against Lipid Hydroperoxide Damage and in Alzheimer\textquotesingles Disease
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Yoo Min-Hyuk,
Xinglong Gu,
Xue-Ming Xu,
Kim Jin-Young,
Carlson Bradley A.,
Patterson Andrew D.,
Cai Huaibin,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале Antioxidants and Redox Signaling, издательство Mary Ann Liebert Inc. (United States), том 12, № 7, с. 819-827
DOI
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2010
Insights into Function, Catalytic Mechanism, and Fold Evolution of Selenoprotein Methionine Sulfoxide Reductase B1 through Structural Analysis
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Aachmann Finn L.,
Sal Lena S.,
Kim Hwa-Young,
Marino Stefano M.,
Gladyshev Vadim N.,
Dikiy Alexander
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 285, № 43, с. 33315-33323
DOI
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2010
Mammalian thioredoxin reductase 1: roles in redox homoeostasis and characterization of cellular targets
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Turanov Anton A.,
Kehr Sebastian,
Marino Stefano M.,
Yoo Min-Hyuk,
Carlson Bradley A.,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Biochemical Journal, издательство Portland Press, Ltd. (United Kingdom), том 430, № 2, с. 285-293
DOI
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2010
Regulation of Selenoproteins and Methionine Sulfoxide Reductases A and B1 by Age, Calorie Restriction, and Dietary Selenium in Mice
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Novoselov Sergey V.,
Kim Hwa-Young,
Hua Deame,
Lee Byung Cheon,
Astle Clinton M.,
Harrison David E.,
Friguet Bertrand,
Moustafa Mohamed E.,
Carlson Bradley A.,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Antioxidants and Redox Signaling, издательство Mary Ann Liebert Inc. (United States), том 12, № 7, с. 829-838
DOI
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2010
Role of selenium-containing proteins in T-cell and macrophage function
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Carlson Bradley A.,
Yoo Min-Hyuk,
Shrimali Rajeev K.,
Irons Robert,
Gladyshev Vadim N.,
Hatfield Dolph L.,
Park Jin Mo
-
в журнале Proceedings of the Nutrition Society, издательство CABI Publishing (United Kingdom), том 69, № 03, с. 300-310
DOI
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2010
Structure–Function Relations, Physiological Roles, and Evolution of Mammalian ER-Resident Selenoproteins
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Shchedrina Valentina A.,
Zhang Yan,
Labunskyy Vyacheslav M.,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Antioxidants and Redox Signaling, издательство Mary Ann Liebert Inc. (United States), том 12, № 7, с. 839-849
DOI
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2010
Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery
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Xu X.M.,
Turanov A.A.,
Carlson B.A.,
Yoo M.H.,
Everley R.A.,
Nandakumar R.,
Sorokina I.,
Gygi S.P.,
Gladyshev V.N.,
Hatfield D.L.
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в журнале Proceedings of the National Academy of Sciences of the United States of America, издательство National Academy of Sciences (United States), том 107, № 50, с. 21430-21434
DOI
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2009
A novel stem loop control element-dependent UGA read-through system without translational selenocysteine incorporation in Drosophila
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Hirosawa-Takamori Mitsuko,
Ossipov Dmitri,
Novoselov Sergey V.,
Turanov Anton A.,
Zhang Yan,
Gladyshev Vadim N.,
Krol Alain,
Vorbrüggen Gerd,
Jäckle Herbert
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в журнале FASEB Journal, издательство Federation of American Societies for Experimental Biology (United States), том 23, № 1, с. 107-113
DOI
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2009
Genetic Code Supports Targeted Insertion of Two Amino Acids by One Codon
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Turanov A.A.,
Lobanov A.V.,
Fomenko D.E.,
Morrison H.G.,
Sogin M.L.,
Klobutcher L.A.,
Hatfield D.L.,
Gladyshev V.N.
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в журнале Science, издательство American Association for the Advancement of Science (United States), том 323, № 5911, с. 259-261
DOI
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2009
Overexpression of methionine-R-sulfoxide reductases has no influence on fruit fly aging
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Shchedrina Valentina A.,
Vorbrüggen Gerd,
Lee Byung Cheon,
Kim Hwa-Young,
Kabil Hadise,
Harshman Lawrence G.,
Gladyshev Vadim N.
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в журнале Mechanisms of Ageing and Development, издательство Elsevier BV (Netherlands), том 130, № 7, с. 429-443
DOI
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2009
Recode-2: new design, new search tools, and many more genes
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Bekaert Michaël,
Firth Andrew E.,
Zhang Yan,
Gladyshev Vadim N.,
Atkins John F.,
Baranov Pavel V.
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в журнале Nucleic Acids Research, издательство Oxford University Press (United Kingdom), том 38, № suppl_1, с. D69-D74
DOI
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2009
Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression
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Carlson Bradley A.,
Yoo Min-Hyuk,
Sano Yasuyo,
Sengupta Aniruddha,
Kim Jin,
Irons Robert,
Gladyshev Vadim N.,
Hatfield Dolph L.,
Park Jin
-
в журнале BMC Immunology, издательство BioMed Central (London), том 10, № 1
DOI
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2009
The selenocysteine tRNA STAF-binding region is essential for adequate selenocysteine tRNA status, selenoprotein expression and early age survival of mice
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Carlson Bradley A.,
Schweizer Ulrich,
Perella Christine,
Shrimali Rajeev K.,
Feigenbaum Lionel,
Shen Liya,
Speransky Svetlana,
Floss Thomas,
Jeong Soon-Jeong,
Watts Jennifer,
Hoffmann Victoria,
Combs Gerald F.,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале Biochemical Journal, издательство Portland Press, Ltd. (United Kingdom), том 418, № 1, с. 61-71
DOI
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2009
X-Ray Fluorescence Microscopy Reveals the Role of Selenium in Spermatogenesis
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Kehr Sebastian,
Malinouski Mikalai,
Finney Lydia,
Vogt Stefan,
Labunskyy Vyacheslav M.,
Kasaikina Marina V.,
Carlson Bradley A.,
Zhou You,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Journal of Molecular Biology, издательство Academic Press (United States), том 389, № 5, с. 808-818
DOI
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2008
A functional link between housekeeping selenoproteins and phase II enzymes
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Sengupta Aniruddha,
Carlson Bradley A.,
Weaver James A.,
Novoselov Sergey V.,
Fomenko Dmitri E.,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале Biochemical Journal, издательство Portland Press, Ltd. (United Kingdom), том 413, № 1, с. 151-161
DOI
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2008
Analysis of Methionine/Selenomethionine Oxidation and Methionine Sulfoxide Reductase Function Using Methionine-Rich Proteins and Antibodies against Their Oxidized Forms†
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Tien Le Dung,
Liang Xinwen,
Fomenko Dmitri E.,
Raza Ashraf S.,
Chong Chom-Kyu,
Carlson Bradley A.,
Hatfield Dolph L.,
Gladyshev Vadim N.
-
в журнале Biochemistry, издательство American Chemical Society (United States), том 47, № 25, с. 6685-6694
DOI
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2008
Functional Analysis of Free Methionine-R-sulfoxide Reductase fromSaccharomyces cerevisiae
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Tien Le Dung,
Lee Byung Cheon,
Marino Stefano M.,
Zhang Yan,
Fomenko Dmitri E.,
Kaya Alaattin,
Hacioglu Elise,
Kwak Geun-Hee,
Koc Ahmet,
Kim Hwa-Young,
Gladyshev Vadim N.
-
в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 284, № 7, с. 4354-4364
DOI
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2008
Functional characterization of alternatively spliced human SECISBP2 transcript variants
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Papp Laura V.,
Wang Junning,
Kennedy Derek,
Boucher Didier,
Zhang Yan,
Gladyshev Vadim N.,
Singh Ravindra N.,
Khanna Kum Kum
-
в журнале Nucleic Acids Research, издательство Oxford University Press (United Kingdom), том 36, № 22, с. 7192-7206
DOI
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2008
MsrB1(Methionine-R-sulfoxide Reductase 1) Knock-out Mice
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Fomenko Dmitri E.,
Novoselov Sergey V.,
Natarajan Sathish Kumar,
Lee Byung Cheon,
Koc Ahmet,
Carlson Bradley A.,
Lee Tae-Hyung,
Kim Hwa-Young,
Hatfield Dolph L.,
Gladyshev Vadim N.
-
в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 284, № 9, с. 5986-5993
DOI
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2008
Platyhelminth Mitochondrial and Cytosolic Redox Homeostasis Is Controlled by a Single Thioredoxin Glutathione Reductase and Dependent on Selenium and Glutathione
-
Bonilla Mariana,
Denicola Ana,
Novoselov Sergey V.,
Turanov Anton A.,
Protasio Anna,
Izmendi Darwin,
Gladyshev Vadim N.,
Salinas Gustavo
-
в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 283, № 26, с. 17898-17907
DOI
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2008
Selenoproteins Mediate T Cell Immunity through an Antioxidant Mechanism
-
Shrimali Rajeev K.,
Irons Robert D.,
Carlson Bradley A.,
Sano Yasuyo,
Gladyshev Vadim N.,
Park Jin Mo,
Hatfield Dolph L.
-
в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 283, № 29, с. 20181-20185
DOI
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2007
Comparative Analysis of Selenocysteine Machinery and Selenoproteome Gene Expression in Mouse Brain Identifies Neurons as Key Functional Sites of Selenium in Mammals
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Zhang Yan,
Zhou You,
Schweizer Ulrich,
Savaskan Nicolai E.,
Hua Deame,
Kipnis Jonathan,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 283, № 4, с. 2427-2438
DOI
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2007
New Developments in Selenium Biochemistry: Selenocysteine Biosynthesis in Eukaryotes and Archaea
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Xue-Ming Xu,
Carlson Bradley A.,
Zhang Yan,
Mix Heiko,
Kryukov Gregory V.,
Glass Richard S.,
Berry Marla J.,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале Biological Trace Element Research, издательство Humana Press, Inc. (United States), том 119, № 3, с. 234-241
DOI
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2007
Novel metabolism in Chlamydomonas through the lens of genomics
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GROSSMAN A.,
CROFT M.,
GLADYSHEV V.,
MERCHANT S.,
POSEWITZ M.,
PROCHNIK S.,
SPALDING M.
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в журнале Current Opinion in Plant Biology, издательство Elsevier BV (Netherlands), том 10, № 2, с. 190-198
DOI
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2007
SelT, SelW, SelH, and Rdx12: Genomics and Molecular Insights into the Functions of Selenoproteins of a Novel Thioredoxin-like Family†
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Dikiy Alexander,
Novoselov Sergey V.,
Fomenko Dmitri E.,
Sengupta Aniruddha,
Carlson Bradley A.,
Cerny Ronald L.,
Ginalski Krzysztof,
Grishin Nick V.,
Hatfield Dolph L.,
Gladyshev Vadim N.
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в журнале Biochemistry, издательство American Chemical Society (United States), том 46, № 23, с. 6871-6882
DOI
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2007
Selective Restoration of the Selenoprotein Population in a Mouse Hepatocyte Selenoproteinless Background with Different Mutant Selenocysteine tRNAs Lacking Um34
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Carlson Bradley A.,
Moustafa Mohamed E.,
Sengupta Aniruddha,
Schweizer Ulrich,
Shrimali Rajeev,
Rao Mahadev,
Zhong Nianxin,
Wang Shulin,
Feigenbaum Lionel,
Lee Byeong Jae,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 282, № 45, с. 32591-32602
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2007
Selenophosphate synthetase 2 is essential for selenoprotein biosynthesis
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Xue-Ming Xu,
Carlson Bradley A.,
Irons Robert,
Mix Heiko,
Zhong Nianxin,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале Biochemical Journal, издательство Portland Press, Ltd. (United Kingdom), том 404, № 1, с. 115-120
DOI
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2007
Selenoprotein expression is essential in endothelial cell development and cardiac muscle function
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Shrimali Rajeev K.,
Weaver James A.,
Miller Georgina F.,
Starost Matthew F.,
Carlson Bradley A.,
Novoselov Sergey V.,
Kumaraswamy Easwari,
Gladyshev Vadim N.,
Hatfield Dolph L.
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в журнале Neuromuscular Disorders, издательство Elsevier BV (Netherlands), том 17, № 2, с. 135-142
DOI
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2007
Structure and Catalytic Mechanism of Eukaryotic Selenocysteine Synthase
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Ganichkin Oleg M.,
Xue-Ming Xu,
Carlson Bradley A.,
Mix Heiko,
Hatfield Dolph L.,
Gladyshev Vadim N.,
Wahl Markus C.
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в журнале Journal of Biological Chemistry, издательство American Society for Biochemistry and Molecular Biology Inc. (United States), том 283, № 9, с. 5849-5865
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2007
The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions
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Merchant S.S.,
Prochnik S.E.,
Vallon O.,
Harris E.H.,
Karpowicz S.J.,
Witman G.B.,
Terry A.,
Salamov A.,
Fritz-Laylin L.K.,
Marechal-Drouard L.,
Marshall W.F.,
Qu L.H.,
Nelson D.R.,
Sanderfoot A.A.,
Spalding M.H.,
Kapitonov V.V.,
Ren Q.,
Ferris P.,
Lindquist E.,
Shapiro H.,
Lucas S.M.,
Grimwood J.,
Schmutz J.,
Cardol P.,
Cerutti H.,
Chanfreau G.,
Chen C.L.,
Cognat V.,
Croft M.T.,
Dent R.,
Dutcher S.,
Fernandez E.,
Fukuzawa H.,
Gonzalez-Ballester D.,
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