Аннотация:The study is focused on the psychological factors that contributed to work performance and satisfaction during the organizational innovations, and is based on the regulatory stress approach [Gaillard & Wientjes, 1994; Leonova, 1989, 2003], which is suitable to reveal the influence of the human functional state (HFS) self-regulation on work efficiency. The research aim - to estimate the predictors of work efficiency under innovations. The diagnostic set of methods included: the Managerial stress survey [Leonova, 2006]; Trust assessment scale [Shaw, 1997, adopted by Kupreichenko, 2008], Strategic approach to coping scales questionnaire [Hobfoll, 1994], adopted by Vodopianova & Starchenkova, 2003. The data on the sample of 814 employees of educational organizations, banks, and call-centers allowed to analyze the predictors of work efficiency in tensed conditions: characteristics of work tasks, fairness of job reward and administration, and the high level of organizational trust. The results are discussed taking into account the organizational restrictions to different coping behavior models. The acquisition of adequate psychological resources (motivational support, means of HFS self-regulation and organizationally not-restricted coping) play a key role in the effective adaptation under innovation pressure. The obtained results are recommended for the elaboration of the interventions, targeted to support high coping capacity of employees and to increase work performance.