|
ИСТИНА |
Войти в систему Регистрация |
ИСТИНА ИНХС РАН |
||
[Stability of opiate receptors of wet and lyophilized preparations of rat brain membranes]статья
Информация о цитировании статьи получена из
Scopus
Дата последнего поиска статьи во внешних источниках: 28 мая 2015 г.
- Авторы: Zaĭtsev S.V., Kurochkin I.N., Sergeeva M.G., Varfolomeev S.D.
- Журнал: Biokhimii∎a (Moscow, Russia)
- Том: 49
- Номер: 7
- Год издания: 1984
- Издательство: IZDATELSTVO NAUKA
- Местоположение издательства: LENINGRADSKOE OTDELENIE MAKAROVA D4, STPETERSBURG, RUSSIA
- Первая страница: 1127
- Последняя страница: 1133
- Аннотация: The effects of incubation of rat brain membranes at 0 degrees C on the specific binding of mu-ligands (naloxone, morphine) and the delta-ligand (D-Ala2, D-Leu5-enkephalin) to opiate receptors were studied. The effects of lyophilization of rat brain membranes on the properties of the opiate receptors were determined. The lyophilized brain membrane preparations revealed an extraordinarily high stability as compared to "wet" membranes. The experimental results suggest that morphine and D-Ala2, D-Leu5-enkephalin binding both to the high affinity and low affinity sites has different nature and point to the utility of stable and standard preparations of lyophilized membranes for the use in the receptor analysis of opiate and opioid peptides.
- Добавил в систему: Сергеева Марина Глебовна