Optimized synthesis of 3′-O-aminothymidine and evaluation of its oxime derivative as an anti-HIV agentстатьяИсследовательская статья
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Дата последнего поиска статьи во внешних источниках: 17 апреля 2018 г.
Аннотация:The synthesis and isolation of 3′-O-aminothymidine oximes have been optimized. Synthesized compounds were characterized by NMR and UV spectral and analytical data. A mixture of previously not reported syn and anti isomers of acetaldoximes was assessed for anti-HIV activity and the prevention of syncytia formation caused by HIV-1 infection