Аннотация:Nasal chondromesenchymal hamartoma (NCMH) is a rare benign tumor of the sinonasal tract
in children with possible orbit and skull base involvement. We present the 57th published
observation of this kind of tumor. A 25-month-old female patient presented with recurrent
mass lesion of the sinonasal tract. According to her history, she had feeding difficulties and
nasal obstruction since birth. She underwent partial resection at eight months of age via
transfacial approach in the local hospital. Due to progression of tumor remnants, a second
surgery was performed using an endoscopic endonasal approach resulting in subtotal resection.
At 12 months of follow-up, a good postoperative result was observed with no signs of tumor
progression despite incomplete resection. Histological and immunohistochemical examination
of the biopsy specimens is presented. Comparison of specimens obtained from each of the two
surgeries showed a difference in histological patterns. Endoscopic endonasal approach is the
mainstay of surgical management. In case of incomplete resection, careful follow-up MRI
studies should be recommended.
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