Effect of natural polysaccharides and oligosaccharides on the cell membrane permeabilityстатья
Информация о цитировании статьи получена из
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Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 20 августа 2018 г.
Аннотация:Glycyrrhizic acid, arabinogalactan, and _cyclodextrin are capable of forming complexes
with various drug compounds significantly enhancing their solubility and bioavailability.
To elucidate the mechanism of action of oligo_ and polysaccharides, the exchange time of
transporting formate ions through the membrane of myeloblastic leukemia cells (K562) was
measured by NMR spectroscopy with the addition of paramagnetic ions. It was found that
glycyrrhizic acid and arabinogalactan substantially increased the membrane permeability.