Estimating equivalent doses of internal radiation for the alpha-emitting radiopharmaceutical Astatine-211статья
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Дата последнего поиска статьи во внешних источниках: 4 февраля 2014 г.
Аннотация:The integral activities of the α-emitting radiopharmaceutical (RP) Astatine-211 are estimated using empirical data on the pharmacokinetics when RP is introduced into the body. The obtained values are compared to the analogous estimates for RP 131I in isotonic solution. Linear energy losses are estimated for different organs and tissues of the human body. The linear quadratic model [1] is used to assess the relative qualitative biological effectiveness of α radiation from 211At. The Medical Internal Radiation Dose Committee (MIRDC) approach is used to analyze equivalent and effectively equivalent doses for the standard adult body.