Cell to cell interactions in the cultures of transformed fibroblasts (strain L) and of normal mouse fibroblasts (Russian)статья
Статья опубликована в журнале из списка RSCI Web of Science
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Статья опубликована в журнале из перечня ВАК
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
Аннотация:The degree of contact inhibition of movement and multiplication in isolated cultures of neoplastic mouse fibroblasts of strain L is similar to that observed in isolated cultures of normal mouse embryo fibroblasts. However, in mixed cultures of the cells of these two types, L fibroblasts form colonies on the top of the normal cell sheet, i.e. they reveal the property characteristic of transformed cells. Results of microcinematographic analysis and of scanning electron microscopy suggest that the abnormal behavior of L cells is due to their defective attachment to the substrate.