Аннотация:A method for the synthesis of manganese dioxide nanoparticles in reverse micelles is developed and
optimized. Nanoparticles are characterized by transmission electron microscopy. An amperometric sensor to
detect hydrogen peroxide ion is developed based on thin films from the obtained manganese dioxide nanoparticles.
The possibility of its use for the electrochemical detection of hydrogen peroxide and its operational and
long-term stability are examined. The effect of measuring the response potential, pH, and the ionic strength of
solution, as well as of interfering compounds, on the results of hydrogen peroxide measurements are studied.
The dependence of response values on the hydrogen peroxide concentration is obtained. The linear range of this
dependence is in the interval from 7.8×10–8 to 7.8×10–4M. The detection limit is 7.8×10–8 M 3σ), and thesensitivity is 922 mA/M · cm2). The possibility of using the developed hydrogen peroxide–sensitive sensor forproducing more complex enzyme amperometric sensors based on oxide reductases is exemplified by a choline
oxidase biosensor.