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The importance of molecular parameters of quaternary ammonium salts in their antigibberellin (retardant) activityстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
- Авторы: Gafurov R.G., Grigor'ev V.Y., Proshin A.N., Chistyakov V.G., Martynov I.V., Zefirov N.S.
- Журнал: Russian Journal of Bioorganic Chemistry
- Том: 30
- Номер: 6
- Год издания: 2004
- Издательство: Maik Nauka/Interperiodica Publishing
- Местоположение издательства: Russian Federation
- Первая страница: 592
- Последняя страница: 598
- DOI: 10.1023/B:RUBI.0000049778.67576.cc
- Аннотация: The importance of six theoretically calculated molecular parameters in the antigibberellin (retardant) activity of quaternary ammonium salts is studied using a regression analysis. A bioassay system based on cell culture of fungus Gibberella fujikuroi is used to determine the activity. In the case of N,N,N-trimethyl-N(2-hydroxyethyl)ammonium chloride (choline) and N,N,N-triethyl-N-(2-hydroxyethyl)ammonium chloride (N,N,N-triethylcholine) derivatives with linear structure, the polarizability, proton acceptor activity, and lipophilicity of these compounds exert the largest effect on the antigibberellin activity. The antigibberellin activity of more sterically hindered N,N-dialkylpiperidinium salts was mainly defined by the steric parameter, while the polarizability, proton acceptor activity, and (through them) lipophilicity exert a lesser effect. Other parameters are of minor importance for the three groups of compounds studied.
- Добавил в систему: Зефиров Николай Серафимович