Эпидемиология на основе анализа сточных вод. Оценка потребления опиоидов

Авторы: Рожанец В.В., Носырев А.Е.
Журнал: Наркология
Том: 16
Номер: 9
Год издания: 2017
Первая страница: 26
Последняя страница: 37
Аннотация: Abstract The subject of the review are data on the prevalence of major opioids, their metabolism, pharmacokinetics and stability in wastewater. The review analyzed the main methods for determining opioids in wastewater and compared the analytical results with epidemiological data. The conclusion is made that the detection of morphine or a specific metabolite of heroin 6-MAM in wastewater does not guarantee the possibility of quantifying the level of heroin intake in the population. At the same time, this approach allows for a qualitative comparison of levels of opioid consumption in different geographical locations and limited collectives, and also, to analyze the temporal trend of their consumption. The main result of the study of the consumption of opioids using wastewater analysis for today is confirmation of the continuous nature of their consumption, which sharply distinguishes them from recreational drugs. Ref. 98. Key words: Epidemiology; wastewater; Wastewater-based epidemiology; Sewage-based epidemiology; Chromatography; Mass spectrometry; Opioids; Morphine; Heroin; Codeine; Methadone; Tramadol; Consumption levels
Добавил в систему: Рожанец Владимир Всеволодович

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