Intraarterial Administration of Verapamil for the Prevention and Treatment of Cerebral Angiospasm

Mikeladze, K.; Okishev, D.; Belousova, O.; Konovalov, A.; Pilipenko, Y.; Ageev, I.; Kaftanov, A.; Shekhtman, O.; Kurdyumova, N.; Tabasaransky, T.; Okisheva, E.; Eliava, S.; Yakovlev, S.

Авторы: Mikeladze KG, Okishev DN, Belousova OB, Konovalov AN, Pilipenko YuV, Ageev IS, Kaftanov AN, Shekhtman OD, Kurdyumova NV, Tabasaransky TF, Okisheva EA, Eliava SS, Yakovlev SB
Журнал: Acta Neurochirurgica, Supplement
Том: 127
Номер: 1
Год издания: 2019
Издательство: Springer Verlag
Местоположение издательства: Germany
Первая страница: 1
Последняя страница: 11
Аннотация: From 2013 to 2017, at the Burdenko Institute of Neurosurgery, intraarterial verapamil for treatment of cerebral vasospasm following intracranial hemorrhage after aneurysm rupture was administered to 35 patients (total 75 procedures). The age from 8 to 77 years. All ruptured aneurysms were treated: in 26 cases with open approach – clipping, in 9 cases with endovascular occlusion. The procedure was carried out from 0-11 days after the operation. Severity of spasm was assessed by angiography and TCDU. Efficacy of the administration was assessed by TCDU one hour after the procedure, and by clinical evaluation of the patient's condition. The dose of verapamil was 15-50 mg (on average 40 mg) per procedure/per carotid pool and depended on the data of TCDU, clinical and radiological picture. The procedure was performed repeatedly (1-5 times) according to the indications and depending on the patient's condition, with an interval of 24 hours. The procedure was effective as a preventive measure for care of patients in the initial stage of cerebral ischemia and was ineffective with a formed focus of ischemia. Endovascular administration of verapamil for treatment of cerebral vasospasm is a safe technique which positively affects the overall recovery of such patients.
Добавил в систему: Окишев Дмитрий Николаевич

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Intraarterial Administration of Verapamil for the Prevention and Treatment of Cerebral Angiospasmстатья

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