AQUEOUS-SOLUTIONS OF POLY-N-ALKYL-SUBSTITUTED ACRYLAMIDES - STRUCTURE AND PROPERTIES RELATED TO TARGETED TRANSPORTстатья
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Дата последнего поиска статьи во внешних источниках: 29 мая 2015 г.
Аннотация:Temperature dependence of structure and properties of poly-N-alkyl-substituted acrylamides and their aqueous solutions has been studied by IR-Fourier spectroscopy technique. For poly-N-alkyl-substituted acrylamides showing lower critical solution temperature, a specific H-bonded ring structure involving alkyl amide units of a polymer and hydroxyl functions of water was discovered. A new approach to the targeted transport of physiologically active compounds was proposed. The approach involves the immobilization of these compounds on activated poly-N-alkyl-substituted acrylamides and heating the delivery site above critical temperature.