Heritability estimation of 2D:4D finger ratio in a Chuvashian population-based sampleстатьяИсследовательская статья
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Дата последнего поиска статьи во внешних источниках: 26 апреля 2019 г.
Аннотация:Abstract
Objectives: The purpose of this study was to evaluate the familial correlations and
heritability of 2D:4D ratio traits using a large population-based sample of ethnically
homogeneous pedigrees from Chuvasha and Bashkortostan Autonomies of
the Russian Federation.
Methods: We calculated the familial correlations and performed a heritability analysis
of 2D:4D ratio traits in a sample of 1541 subjects (803 men and 738 women,
mean age 47.78 ± 16.89 years, range 18-90 years).
Results: Familial correlations of 2D:4D ratio traits showed no significant correlation
for spouses; however, parent-offspring (0.15-0.28, P < .001) and sibling correlations
(0.13-0.38, P < .009) were found to be significant. Heritability (H2) of
visual classification of 2D:4D ratio was 0.36 for the left and 0.28 for the right hand;
finger ratio was 0.55 and 0.66, respectively; the ray ratio was 0.49 and 0.59,
respectively, thus indicating the existence of a clear familial aggregation of 2D:4D
ratio variation in the Chuvashian pedigrees, which cannot be explained only by
common environmental effects.
Discussion: Results of our study suggest familial aggregations of finger ratio variation
(for all traits) in Chuvashian pedigrees. No evidence of assortative mating was
found.