Parallel Merging Method to Integrate Different Genome Assemblies

Автор: Kirill Romanenkov
Сборник: 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
Год издания: 2015
Место издания: Washington, DC
Первая страница: 1461
Последняя страница: 1464
DOI: 10.1109/BIBM.2015.7359891
Аннотация: In this paper research in the field of application multiprocessor systems for genome assemblies reconciliation has been carried out. A large number of algorithmic approaches aimed to solve the task of de novo assembly from short reads, however the results of their work on the same raw data often differ essentially. A parallel algorithm for merging two or more assemblies without relying on a reference genome is presented. Due to the large data volume the computations in the distributed memory model on computational cluster are required. The proposed method integrates a combination of draft assemblies reducing resulting contigs fragmentation. Sequential version of the algorithm is implemented in C/C++ and is available at https://bitbucket.org/kromanenkov/gar.
Добавил в систему: Романенков Кирилл Владимирович

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