Mechanical zona pellucida removal of vitrified-warmed human blastocysts does not affect the clinical outcome

Авторы: Kirienko K.V., Apryshko V.P., Naumova A.A., Kharitonova M.A., Klepukov A.A., Bolt A.I., Ermilova I.Y., Mironova A.G., Bozina Y.V., Lebedeva E.B., Simonenko E.Y., Vajta G., Yakovenko S.A.
Журнал: Reproductive BioMedicine Online
Том: 29
Номер: 5
Год издания: 2019
Издательство: Reproductive Healthcare Ltd
Местоположение издательства: United Kingdom
Первая страница: 745
Последняя страница: 749
DOI: 10.1016/j.rbmo.2019.06.003
Аннотация: Research Question: Does complete mechanical removal of the zona pellucida modify the outcome of transfer of vitrified-warmed humanblastocysts? Design:In a prospective randomized controlled study:a total of 419couples were allocated to either zona pellucida-free (n=209)or zona intact(n=210)vitrified-warmed embryo transfer.Main outcome measures included clinical pregnancy, implantation and ongoingpregnancy rates.Results:Transfer ofzona pellucida-free blastocysts resulted in clinical pregnancy, implantation and ongoing pregnancy rates (35,9%, 33,9% and 32,1%, respectively) similar to those achieved with zona intact control embryos (39%, 36,4% and 33,1%, respectively).Conclusion:Total mechanical removal of the zona pellucidadid not affectthetested parametersof clinical outcomes.
Добавил в систему: Симоненко Екатерина Юрьевна

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