Effects of lipoic acid on proliferation and apoptosis of liver cells in rats with metabolic stressстатья
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Дата последнего поиска статьи во внешних источниках: 9 июня 2016 г.
Аннотация:Lipoic acid stimulated expression of heat shock proteins 25, 70, and 90 in liver cells of Wistar rats with metabolic stress (5 days of food deprivation followed by complete resumption of nutrition). Lipoic acid in a dose of 25 mg/kg reduced proliferation of hepatic lymphocytes during fasting, while after resumption of feeding it stimulated hepatocyte proliferation due to differentiated regulation of the expression of cyclin D1 and Rb protein in these cell populations.