Mathematical modeling of alveolar ventilation and gas exchange during treadmill stress testsтезисы доклада

Дата последнего поиска статьи во внешних источниках: 24 января 2020 г.

Работа с тезисами доклада


[1] Golov A., Simakov S., Timme E. Mathematical modeling of alveolar ventilation and gas exchange during treadmill stress tests // EXPERIMENTAL AND COMPUTATIONAL BIOMEDICINE: Russian Conference with International Participation in memory of Professor Vladimir S. Markhasin.Ekaterinburg, April 10-12, 2016. — Ural Federal University Ekaterinburg, 2016. — P. 32. Physiological tests with incremental or ramp protocols are the most common methods of estimation the level of aerobic capacity. A cardiorespiratory system is one of limiting factors of athlete performance. The increase in gas exchange can be achieved either by increasing the frequency of the respiratory cycles, or by increasing the tidal volume. However, at higher frequencies above a certain level, there is a noticeable drop in the efficiency of O2 delivery and CO2 removal. In this work the method of numerical simulation of alveolar ventilation and muscle gas exchange kinetics taking into account the individual topology trachea-bronchial tree (based on MRI data) of the athlete and using the experimental data of O2 uptake and CO2 are proposed. This model can be used to estimate the body exercise tolerance in terms of efficiency of gas exchange in the lungs, to determine the body response to different types of work rate intensity and to investigate respiratory patterns.

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