Kinetics of the release of antibiotics from chitosan-based biodegradable biopolymer membranesстатья
Информация о цитировании статьи получена из
Scopus,
Web of Science
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 26 августа 2016 г.
Аннотация:A process for manufacture of chitosan-based biodegradable biopolymer membranes suitable for medical applications was developed. A technology for inclusion of broad spectrum antibiotics into the chitosan membranes was elaborated. The effects of pH of the solution surrounding the membranes and the initial solvent chosen for chitosan on the kinetics of release of antibiotics from the membranes were studied. It was demonstrated that the kinetics of drug release from the chitosan-based biodegradable biopolymer membranes depends on the properties of substance immobilized in the membrane, the membrane manufacture process, and extraction conditions.