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Noninvasive glucose sensing in scattering media using OCT, PAS, and TOF techniquesстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Дата последнего поиска статьи во внешних источниках: 26 сентября 2016 г.
- Авторы: Alarousu E., Hast J., Kinnunen M., Kirillin M., Myllylä R., Plucinski J., Popov A., Priezzhev A., Prykäri T., Saarela J., Zuomin Z.
- Сборник: Proceedings SPIE
- Серия: Saratov Fall Meeting 2003: Optical Technologies in Biophysics and Medicine V
- Том: 5474
- Год издания: 2004
- Место издания: SPIE - The International Society for Optical Engineering Bellingham, WA, United States
- Первая страница: 33
- Последняя страница: 41
- DOI: 10.1117/12.578321
- Аннотация: In this paper, optical measurement techniques, which enable non-invasive measurement, are superimposed to glucose sensing in scattering media. Used measurement techniques are Optical Coherence Tomography (OCT), Photoacoustic spectroscopy (PAS) and laser pulse Time-of-Flight (TOF) measurement using a streak camera. In parallel with measurements, a Monte-Carlo (MC) simulation models have been developed. Experimental in vitro measurements were performed using Intralipid™ fat emulsion as a tissue simulating phantom for OCT and TOF measurements. In PAS measurements, a pork meat was used as a subject but also preliminary in vivo measurements were done. OCT measurement results show that the slope of the OCT signal’s envelope changes as a function of glucose content in the scattering media. TOF measurements show that the laser pulse full width of half maximum (FWHM) changes a little as function of glucose content. An agreement with MC-simulations and measurements with IntralipidTM was also found. Measurement results of PAS technique show that changes in glucose content in the pork meat tissue can be measured. In vivo measurements with a human volunteer show that other factors such as physiological change, blood circulation and body temperature drift may interfere the PA response of glucose.
- Добавил в систему: Приезжев Александр Васильевич