Effect of cobalamin derivatives on DNA synthesis in cells of Propionibacterium freudenreichii subsp. shermanii

Авторы: Iordan E.P., Petukhova N.I., Vorob'eva L.I.
Журнал: Nauchnye doklady vysshe∎ shkoly. Biologicheskie nauki
Номер: 1
Год издания: 1987
Издательство: Biologicheskie Nauki
Местоположение издательства: Moskva, Russia (Federation)
Первая страница: 5
Последняя страница: 10
Аннотация: The increase of DNA-synthesis rate (according incorporation [8-14C]adenine) in B12-deficient cells Propionibacterium shermanii as a result of different cobalamines adding into the cell suspension including metoxyethyladenile analog of adenozilcobalamin and some components of vitamin B12 molecule has been found. The DNA-synthesis rate in B12-deficient cells is nearly twice lower as compared with one in B12-normal cells. Considerable stimulative effect (80-100%) was provided with coenzyme forms of cobalamin. The data confirm the participation of vitamin B12 in DNA-synthesis in Propionibacterium cells.
Добавил в систему: Воробьева Лена Ивановна

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