Axotomized neurons of the pteropod mollusc Clione limacina develop novel sites of transmitter release in the absence of their normal muscle targetстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
Аннотация:Neural network for rhythmic wing movements in the swimming molluse Clione limacina is a well-studied system. After nerve transection the efferent wing neurons cannot reach muscles and consequently display intensive central sprouting. In the present work it was shown that two types of efferent neurons with different neurotransmitters: acethylcholinergic locomotor motoneurons and serotonergic modulatory efferent neurons - when deprived of their normal targets, release their neurotransmitter intended for peripheral muscles, in the unusual compartment - neuropile. Such 'unauthorized' release of neurotransmitter may cause nervous system dysfunctions in the damaged brain of other animals. (C) 1999 Elsevier Science Inc. All rights reserved.