Effect of Ultrashort Electric Pulses on Nanocomposite Liposomes in Aqueous Mediumстатья
Информация о цитировании статьи получена из
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Дата последнего поиска статьи во внешних источниках: 17 июня 2020 г.
Аннотация:Nanocomposite liposomes with modified structure containing functional conducting nanoparticles bound to both inner and outer surface of the liposomal membrane are fabricated. Effect of ultrashort electric-field pulses with a duration of less than 10 ns and a field strength of about 10 kV/cm on an aqueous suspension of the liposomes containing encapsulated model substance (NaCl) leads to decapsulation and a corresponding increase in the conductivity of the aqueous medium. Selectivity of the effect is provided by the presence of functional nanoparticles on both surfaces of the liposomal membranes. A theoretical model of a nonthermal effect of ultrashort electric pulses on the nanocomposite liposomes with modified structure is proposed to account for destruction of the liposomal membrane.