Osteoconductive ceramics based on Ca3-xNa2x(1-y)K2xy(PO4)2: fabrication and resorbability testing

Авторы: Putlayev V., Evdokimov P., Orlov N., Klimashina E., Safronova T., Garshev A.
Сборник: Biomaterials for Healthcare. Biomaterials For Tissue And Genetic Engineering And The Role Of Nanotechnology
Тезисы
Год издания: 2016
Место издания: CNR edizioni Roma, Italy
Первая страница: 119
Последняя страница: 122
Аннотация: Biomaterials based on hydroxyapatite (HAp, Ca10(PO4)6(OH)2) or/and more soluble tricalcium phosphate (TCP, Ca3(PO4)2); are widely used for bone tissue engineering, but still does not meet all the clinical requirements (bioresorption, strength, fracture toughness, etc.). We expected to elaborate double/ternary phosphates of calcium and alkali metals (sodium and potassium) for ceramic bone scaffolds production with enhanced level of solubility matching that of materials based on HAp or/and TCP. 3D-printing is a promising technique to fabricate bone scaffolds of complex shape. Ceramic scaffolds with Gyroid structure and high porosity obtained via stereolithography can enhance osteoconductive properties. Results and Discussion Ceramics with pre-determined pore size (50 mkm and more) and overall porosity >80% with Gyroid architecture were fabricated via stereolithography. Gyroid structure is used to enhance osteoconductive properties of the ceramic scaffolds due to its hgh permeability.
Добавил в систему: Климашина Елена Сергеевна

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