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Recombinant Human Bone Growth Factor BMP-2 Synthesized in Escherichia coli Cells. Part 2: From Combined Use with Other Protein Factors in Animal Models to Application in Medicineстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 21 октября 2020 г.
- Авторы: Gromov A.V., Poponova M.S., Karyagina A.S.
- Журнал: Molecular Genetics, Microbiology and Virology
- Том: 35
- Номер: 2
- Год издания: 2020
- Издательство: Allerton Press Inc.
- Местоположение издательства: United States
- Первая страница: 61
- Последняя страница: 68
- DOI: 10.3103/s0891416820020056
- Аннотация: This review is devoted to current approaches to the combined use of BMP-2 with other protein factors to increase osteoinductivity of recently developed materials. The current trend is to create materials with a low BMP-2 concentration that are efficient in osteoinduction and provide continuous protein release. A number of medications have been developed in Russia and South Korea on the basis of BMP-2 synthesized in E. coli cells. The first experience of their use in orthopedics, traumatology, spinal surgery, and dental implantology showed promising results. Also, the possibility of the recombinant BMP-2 use in ophthalmology, and oncology, as well as osteoarthritis treatment, was studied.
- Добавил в систему: Карягина-Жулина Анна Станиславовна