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HEAT SHOCK PROTEIN HSP70 IN OXIDATIVE STRESS IN APNEA PATIENTSстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 30 декабря 2020 г.
- Авторы: Madaeva I.M., Kurashova N.A., Semenova N.V., Ukhinov E.B., Kolesnikov S.I., Kolesnikova L.I.
- Журнал: Bulletin of Experimental Biology and Medicine
- Том: 169
- Номер: 5
- Год издания: 2020
- Издательство: Springer Nature
- Местоположение издательства: Switzerland
- Первая страница: 695
- Последняя страница: 697
- DOI: 10.1007/s10517-020-04957-9
- Аннотация: We studied the level of heat shock protein HSP70 under conditions of oxidative stress in 47 patients with apnea. The control group included 13 healthy subjects without verified apnea. Blood serum, plasma, and erythrocyte hemolysate were used to determine LPO and anti-oxidant protection components by spectrophotometrical and spectrofluorometrical methods. HSP70 was assayed by ELISA. A direct relationship was established between the intensity of oxidative stress and HSP70 expression in patients with apnea. Quantitative determination of HSP70 can be used as a molecular marker in the early diagnosis and prognosis of the development of various pathological conditions in hypoxia.
- Добавил в систему: Колесников Сергей Иванович