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Analogy-based protein structure prediction: II. Testing of substitution matrices and pseudopotentials used to align protein sequences with spatial structuresстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 15 июля 2021 г.
- Авторы: Lobanov M.Yu, Finkel'shtein A.V.
- Журнал: Molecular Biology
- Том: 43
- Номер: 4
- Год издания: 2009
- Издательство: Maik Nauka/Interperiodica Publishing
- Местоположение издательства: Russian Federation
- Первая страница: 677
- Последняя страница: 684
- DOI: 10.1134/s0026893309040207
- Аннотация: The results of testing the recognition ability of various amino acid substitution matrices and manifold (both extracted from the literature and of our own design) pseudopotentials intended for the recognition of protein structures and sequence-to-structure alignments are described. The numerical estimates of the recognition ability of various substitution matrices and pseudopotentials were obtained for different levels of protein structure similarity. It is demonstrated that substitution matrices work much better than pseudopotentials at a high degree of sequence similarity of spatially similar proteins; however, some pseudopotentials outdo substitution matrices at a low level of sequence similarity between analogous proteins.
- Добавил в систему: Финкельштейн Алексей Витальевич