Аннотация:The narrowing of the immunoglobulin heavy chain variable region (IGHV) gene repertoire is a feature of chronic lymphocytic leukemia (CLL) and several other B-cell malignancies. In this study we examined the IGHV gene sequences of 1937 patients with the most common B-cell lymphomas. We present a detailed comparison of B-cell receptor gene repertoires between CLL and other malignancies in patients from Russia and other populations.