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BRCA1 Expression Regulation and its Role as a Biomarker of Cancerстатья
- Автор: Shestakova Elena A.
- Журнал: Journal of Investigative Genomics
- Том: 2
- Номер: 5
- Год издания: 2015
- Первая страница: 00037
- DOI: 10.15406/jig.2015.02.00037
- Аннотация: Tumor suppressor BRCA1 prevents the development of several cancers, mainly breast and ovarian cancer. The main function of BRCA1 is the repair of DNA damage through homology recombination. The disruption of this BRCA1 function leads to the development of several oncological diseases, in particular, breast cancer, ovarian cancer and also non-small cell lung cancer. Recently, it became clear that BRCA1 can serve as a prognostic marker of the course of several oncological diseases and as a predictive marker of platinum-based therapy.
- Добавил в систему: Шестакова Елена Анатольевна
Прикрепленные файлы
| № | Имя | Описание | Имя файла | Размер | Добавлен |
|---|---|---|---|---|---|
| 1. | Полный текст | Editorial | Shestakova_EA_BRCA1_JIG_02_00037.pdf | 281,0 КБ | 19 сентября 2021 [ShestakovaEAn] |