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Iron ion doped tricalcium phosphate coatings improve the properties of biodegradable magnesium alloys for biomedical implant applicationстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 20 октября 2021 г.
- Авторы: Antoniac I.V., Filipescu M., Barbaro K., Bonciu A., Birjega R., Cotrut C.M., Galvano E., Fosca M., Fadeeva I.V., Vadalà G., Dinescu M., Rau J.V.
- Журнал: ADVANCED MATERIALS INTERFACES
- Год издания: 2020
- Первая страница: 2000531
- Последняя страница: 2000531
- Аннотация: Iron-substituted tricalcium phosphate (Fe-TCP) (about 1 wt%) coatings are deposited on biodegradable Mg-Ca alloys to improve their corrosion resistance. Pulsed laser deposition technique is used for coating preparation. The 2 µm thick coatings are uniformly deposited. (Ca+Fe)/P ratio for the Fe-TCP coatings is close to the stoichiometric value. Coated and uncoated Mg-Ca alloys are subjected to electrochemical tests to investigate the influence of the coatings on their corrosion resistance in simulated body fluid (SBF). Tafel curves corresponding to coated and uncoated Mg-Ca alloy samples in SBF show that the most electropositive corrosion potential is reached for the Fe-TCP-coated Mg-Ca deposited at 300 °C. From the obtained and calculated values of the electrochemical parameters it follows that this sample possesses the best characteristics: it has the smallest porosity and the highest protective efficiency in SBF. Equine adipose tissue-derived mesenchymal stem cells are used for 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test and osteogenic differentiation study. Microbiology tests are performed with Escherichia coli (E. coli) (Gram−) and Staphylococcus aureus (Gram+) bacteria strains. The Fe-TCP-coated Mg-Ca deposited at 300 °C is characterized by the best cytocompatibility and good ability to inhibit the growth of E. coli and is recommended for biomedical implant applications.
- Добавил в систему: Фадеева Инна Вилоровна