Аннотация:Results of 527 liver resection for metastatic colorectal tumors and 225 resection in primary liver cancer patients are presented. Morbidity in the first group was noticed in 166 (31.5%) cases. Liver failure was the most frequent one (83 - 15.7%), dyed - 17 (3.2%) patients. Among those who underwent preoperative portal vein embolysation no morbidity and mortality rate was noticed. Mean blood loss came to 1396.2 ml. In extended liver resection applying liver hanging maneuver in 12 cases mean blood loss significantly decreased in comparison with standard method group (673.4 ml versus 1439,4 ml; р = 0.002). Application of the Habib Sealer also decreases the blood loss in economy as well as in extended liver resections. Besides bile fistula rate in economy resection group increased. In the liver resection accompanied with unresectable tumor destruction group mortality rate came to 3.2% and morbidity rate - 25.8%. 5 years survival after metastatic colorectal canser resection came to 37.4% and life median - 47 months. Portal lymph node metastasis is unfavorable prognostic factor, however in such cases 5 year survival got at 6.4%. Accomplishing extended liver resections for less then 10 cm solitary metastasis life median reached 50 months, economy resection - 38 months (difference in statistically significant, p = 0.32). After the liver resection for hepatocellular carcinoma postoperative morbidity rate came up to 44.6%, more often occurred liver failure (15.1%). Mortality came to 5,7%. 5% and 10%years survival after curative resections came to 53.5% and 37,3% correspondingly, median OS - 62 months.