Аннотация:Introduction: Patients are characterized by locally advanced tumours in 70-80% of cases at presentation. Thus, the possibilities for curing and surgicaltreatment are limited. Total glossectomy, which involves tongue base resection, is associated with severe and permanent disabilities. Total glossectomyleads to severe dysphagia, alalia and social maladjustment. A number of issues motivated us to develop a new method of surgical treatment of locallyadvanced base of tongue cancer.Objective: To introduce new opportunities for surgical treatment of locally advanced cancer of the tongue base.Materials and Methods: Glossectomy was accomplished in five patients suffering from tongue cancer and admitted to N.N. Blokhin National Medicaland Research Center of Oncology. Swallowing and speech were preserved in all 5 cases.Results: We developed a new technique of surgical treatment of locally advanced cancer of the tongue base.Conclusion: The developed surgical technique allows early rehabilitation. Patients are able to breath effortlessly, swallow and speak. Permanenttracheostomy and PEG tubes are not necessary. All patients remained socially active.