Аннотация:The results of the experiments on the dynamics of laser produced vapor plumes show peculiarities in angular distribution of components, which lead to a change in stoichiometry of deposited films and to other effects, for example, a sharpening effect within the plumes produced by MALDI technique. A theoretical analysis of the MALDI plumes expansion is done on the basis of special solution of gas dynamic equations. This permits to explain experimental data and simulate many important characteristics, i.e. TOF spectra, film thickness profile of deposited material, etc.