Silicon-Vacancy Nanodiamonds as High Performance Near-Infrared Emitters for Live-Cell Dual-Color Imaging and Thermometry

Авторы: Liu Weina, Alam Md Noor A., Liu Yan, Agafonov Viatcheslav N., Qi Haoyuan, Koynov Kaloian, Davydov Valery A., Uzbekov Rustem, Kaiser Ute, Lasser Theo, Jelezko Fedor, Ermakova Anna, Weil Tanja
Журнал: Nano Letters
Год издания: 2022
Издательство: American Chemical Society
Местоположение издательства: United States
DOI: 10.1021/acs.nanolett.2c00040
Аннотация: Nanodiamonds (NDs) with color centers are excellent emitters for various bioimaging and quantum biosensing applications. In our work, we explore new applications of NDs with silicon-vacancy centers (SiV) obtained by high-pressure high-temperature (HPHT) synthesis based on metal-catalyst-free growth. They are coated with a polypeptide biopolymer, which is essential for efficient cellular uptake. The unique optical properties of NDs with SiV are their high photostability and narrow emission in the near-infrared region. Our results demonstrate for the first time that NDs with SiV allow live-cell dual-color imaging and intracellular tracking. Also, intracellular thermometry and challenges associated with SiV atomic defects in NDs are investigated and discussed for the first time. NDs with SiV nanoemitters provide new avenues for live-cell bioimaging, diagnostic (SiV as a nanosized thermometer), and theranostic (nanodiamonds as drug carrier) applications.
Добавил в систему: Узбеков Рустем Эдуардович

	ИСТИНА	Войти в систему Регистрация
	ИСТИНА ИНХС РАН
	Главная Поиск Статистика О проекте Помощь

ИСТИНА