Some priorities and fundamental concepts in contemporary issues of ecological and molecular toxicology, biogeochemistry and ecological geochemistry:  ecotoxicants including membranotropic xenobiotics and metals

Kotelevtsev, S.V.; Orlov, S.N.; Matorin, D.N.; Novikov, K.N.; Sadchikov, A.P.; Smurov, A.V.; Ermakov, V.V.; Ostroumov, S.A.

Авторы: Kotelevtsev S.V., Orlov S.N., Matorin D.N., Novikov K.N., Sadchikov A.P., Smurov A.V., Ermakov V.V., Ostroumov S.A.
Сборник: Ecological Studies, Hazards and Solutions
Редактор: Горшкова Ольга Михайловна
Серия: Ecological Studies, Hazards, Solutions
Том: 19
Тезисы
Год издания: 2013
Место издания: MAKS Press, Moscow
Первая страница: 122
Последняя страница: 124
Аннотация: Kotelevtsev S.V., Orlov S.N., Matorin D.N., Novikov K.N., Sadchikov A.P., Smurov A.V., Ermakov V.V., Ostroumov S.A. Some priorities and fundamental concepts in contemporary issues of ecological and molecular toxicology, biogeochemistry and ecological geochemistry: ecotoxicants including membranotropic xenobiotics and metals. // Ecological Studies, Hazards, Solutions, 2013, vol. 19, p.122-124. http://istina.msu.ru/publications/article/4492419/ M.V.Lomonosov Moscow State University, Moscow, Russian Federation V.I. Vernadsky Institute of Geochemistry, Moscow, Russian Federation Environmental pollution of the biosphere and ecotoxicants became an issue of high priority in modern science. Our experimental studies [1-22] demonstrated a variety of biological effects produced by xenobiotics and ecotoxicants. The priority biological, toxicological and biogeochemical effects and phenomena which are worth further studying include: (1) Genotoxic effects (e.g., the effects that are being detected by Ames test with Salmonella typhimurium and rat microsomes) [8, 10, 12] . (2) Various membranotropic effects [4]. (3) A variety of macroscopic effects that could serve as a basis for bioassay, toxicity testing and hazard assessment [19-22]. (4) Effects associated with immobilization of ecotoxicants (heavy metals, rare earth elements) by samples of biogenic material [23]. (5) Toxic effects and immobilization phenomena which are found in experiments with nanomaterials that can pollute the environment [24]. Another recent result was a discovery of toxicity of nanoparticles of gold in a system with aquatic plants (Kotelevtsev, Orlov, Poklonov, Ostroumov, in press). (6) Phenomena of chemical-biotic interactions that could be used in remediation of polluted environment. These six groups of effects and phenomena that were listed above exemplify some of the modern priorities in studies of interdisciplinary issues of chemical-biotic interactions, ecotoxicology, and ecological and molecular geochemistry. These studies could complement modern achievements in biomedical research of xenobiotics and in environmental toxicology of the biosphere. Acknowledgements. The work of some of the co-authors was supported by grants from a variety of grant-giving foundations and institutions including RFFI (Russian Foundation for Fundamental Research), Fulbright Foundation and others. Literature. 1. Котелевцев С. В., Стволинский С.Л., Бейм А.М. Эколого-токсикологический анализ на основе биологических мембран. - М.: МГУ, 1986. -105 с. 2. Lindström-Seppä P., Huuskonen S., Räänen T., Hänninen O., Kotelevtsev S., Stepanova L., Mikkelson P. Toxicity and mutagenicity of waste waters from Baikalsk pulp and paper mill: evaluation of pollutant contamination in Lake Baikal // Marine Environmental Research. 1998. Т. 46. № 1-5. С. 273-277. 3. Whitehead A., Anderson S.L., Kuivila K.M., Orlando J.L., Kotelevtsev S. Genotoxicity in native fish associated with agricultural runoff events // Environmental Toxicology and Chemistry. 2004. Т. 23. № 12. С. 2868-2877. 4. Kotelevtzev S.V., Nagdaliev F.F., Sadchikov A.P. Bio-assay and bioindication at ecological analysis of the environment. Publishers: Alteks, Moscow, 2011, 174 p. 5. Kotelevtsev S.V., Matorin D.N., Sadchikov A.P. Ecological-Toxicological analysis of plant communities in aquatic ecosystems. Altex Press, Moscow. 2012. 182 p. 6. Novikov K.N., S.V. Kotelevtsev, Yu.P.Kozlov. The free-radical processes in biological systems under the influence of environmental factors. - Moscow: Publishing House of People's Friendship University, 2011. - 199 p. ISBN 978-5-209-03659-3. 7. 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