|
ИСТИНА |
Войти в систему Регистрация |
ИСТИНА ИНХС РАН |
||
Alpha oscillations in the subthalamic nucleus interfere with motor functions in patients with parkinson’s diseaseстатья
- Авторы: Belova E.M., Semenova U., Sedov A., Gamaleya A.A., Tomskiy A.A.
- Сборник: Advances in Cognitive Research, Artificial Intelligence and Neuroinformatics. Proceedings of the 9th International Conference on Cognitive Sciences, Intercognsci-2020, October 10-16, 2020, Moscow, Russia
- Серия: Advances in Intelligent Systems and Computing (AISC)
- Том: 1358
- Год издания: 2021
- Издательство: Springer International Publishing AG
- Местоположение издательства: Cham, Switzerland
- Первая страница: 560
- Последняя страница: 570
- DOI: 10.1007/978-3-030-71637-0_65
- Аннотация: Basal ganglia electrophysiological oscillations are extensively studied. While beta oscillations are considered to contribute to motor dysfunction inParkinson’s Disease (PD), alpha oscillations have not been the focus of researchers.This study was inspired by observing stable oscillations in the alpha range during deep brain stimulation (DBS) surgeries in Parkinsonian patients. Hence, weaimed to investigate the role of alpha oscillations in motor performance of PD. Werecorded local field potentials during DBS surgeries. We identified alpha and betaoscillation peaks and their localization, sensitivity to motor tests, and correlationbetween the oscillation power in both bands with symptoms severity on the contralateral side of the body. The alpha oscillation area was located ventrally to thebeta oscillation area. Beta, but not alpha oscillations were sensitive to voluntarymovements. Alpha oscillations were associated with a more severe bradykinesiascore on the contralateral side of the body. We may conclude that alpha oscillationsmay interfere with motor performance in a different manner than beta. The highstability of alpha oscillations may contribute to both the insensitivity to motortests and manifestation of bradykinesia.
- Добавил в систему: Гамалея Анна Александровна